Adrenal Medulla
Synopsis of Adrenal Medulla
The adrenal medulla is the inner core of the adrenal gland and plays a critical role in the body’s short-term stress response. Unlike the outer adrenal cortex, which produces steroid hormones, the adrenal medulla is composed of neuroendocrine chromaffin cells and functions as an extension of the sympathetic nervous system. It secretes catecholamines—primarily epinephrine (adrenaline), norepinephrine (noradrenaline), and small amounts of dopamine—directly into the bloodstream in response to acute stress.
These hormones prepare the body for the “fight-or-flight” response by increasing heart rate, dilating airways, elevating blood pressure, increasing blood glucose levels, and redirecting blood flow to muscles. The adrenal medulla is activated via nerve signals from the hypothalamus through the sympathetic preganglionic fibers, making it a rapid-response system for immediate physical and psychological stressors.
Medically, overactivity of the adrenal medulla can be associated with pheochromocytoma (a rare tumor leading to excess catecholamine production), whereas underfunction may manifest in cases of sympathetic nervous system suppression or extreme fatigue.
Natural remedies to support Adrenal Medulla
Acute stress reduction: Breathing exercises and cold exposure training help modulate adrenaline spikes.
Blood sugar regulation: Eating regular meals with protein and fat prevents glucose crashes that can trigger overactivation.
Physical activity: Interval training and moderate exercise can condition appropriate adrenal medulla output.
Sleep and circadian rhythm alignment: Restorative sleep supports healthy nervous system response and adrenal resilience.
Nerve tonics: Calming nervines and adaptogens help moderate the reactivity of the sympathoadrenal system.
Ingredients
These raw ingredients are often used in alternative medicine to support Adrenal Medulla.
acetyl l-carnitine
adrenal cortex
amino acids
ashwagandha
bovine
caffeine
chamomile
eleuthero
ginseng
guarana
guayusa
l-tyrosine
lion's mane
magnesium
Acetyl-L-Tyrosine
pantothenic acid (vitamin B5)
phosphatidylserine
rhodiola
SAMe (s-adenosyl-l-methionine disulfate p-toluensulfate)
valerian root
vitamin B
vitamin B6
vitamin C
whole adrenal glandular
zinc
sodium salt
zanthoxylum
hypothalamus
yohimbe
sea salt
11-Keto-Androstenetrione
1,3-DMAA
1,3-DMAA
DMPX
11-hydroxy yohimbine
1,3,7-Trimethylpurine-2,6-dione
11-Ketotestosterone
3-Alpha-Hydroxyetioallocholan-17-one
3-Ketosteroid
3-desoxy-7-KETO-DHEA
5,7-Dimethoxyflavone
6, 17 keto etiocholeva-3-ol 3, 17 ketoetiochol-triene
Adrue
Animal Tissue
Adrenals
Adrenal
American Pawpaw
Adrenosterone
Alkaloid (unspecified)
Acetyl L-Tyrosine
Adrenergic amines
Active Amines
Adrenaline
American Ginseng
Alkaloids
Adrenals
Acetyl-L-Tyrosine
alkaloid
Adrenal extract
Animal protein
blend (herb/botanical)
botanical (unspecified)
Bitter orange
Bovine (unspecified)
Blend (Mineral)
Beta Methylphenethylalamine
blend (herb/botanical)
Bruteridine
Bovine (not specified)
Beta-Methylphenylethylamine
Coffee
Citrin
Caffeine pterostilbene
Coenzyme A
Catecholamine
Caffeine alpha-ketoglutarate
Chlorogenin
Complex
Coca
Caffeine
Coffee (mixed)
Carbohydrate
Dioscorea hondurensis
Dimethylamylamine
Dimethylhexylamine (DMHA)
Dimethylpentylamine
Dimethylphenethylamine
Dodeca-2E, 4E-Dienoic Acid Isobutylamide
DL-phenylalanine
Dioscorea nipponica
Dimethyl phenethylamine
Dodeca-2E, 4E, 8Z, 10Z/Etetraenoic Acid Isobutylamide
Ephedra
Epistane
Exphedrine HCl
Eurypeptides
Epimedium
Eleuthero Root
Eleutherococcus gracilistylus
Eleuthero
Eurypeptides
Epimedium extract
Eleutherococcus senticosus
Ephedrine
Eleutheroside
food additive (unspecified)
Fungus (unspecified)
Furanosteroid
Genseng (not specified)
Ginsenosides
Gland (unspecified)
Ginsenosides (unspecified)
Ginseng
Glandular Tissues
Gland (mixed)
Guaranine
Ginseng (unspecified)
Guayusa
Guarana
Ginsenoside
Gland (mixed)
Higenamine
Holy Basil Herb
Hypothalamus
Halostachine
Hoenelen
Holy Basil
Hypothalamus protein
Hordenine
Isopropylnorsynephrine
Isopropyloctopamine
Jungli-bean
Kola Nut
Ketosterone
L-Tyrosine
Laxosterone
Lithium
Methylhexaneamine
Medulla
mineral (unspecified)
Methylxanthine (unspecified)
Methylphenethylamine
Methylsynephrine
Ma Huang
Methylhexanamine
N-Acetyl-Tyrosine
N-Acetyl Tyrosine
Nicotine
Norepinephrine
N-Methyltyramine
N-methyl Tyramine
Octodrine
Oxedrine
Oxyephedrine
Octopamine
peptides (unspecified)
Progenin III
Paraxanthine
Panax Ginseng
Panax Pseudoginseng
Peptides (unspecified)
Pig
Panax Notoginseng
Porcine
plant (unspecified)
Poly-thyronine
Pig
Parenchyma
Pantothenic Acid (Vitamin B5)
Rhodola crenulata
Rosabin
Rutacaerpine
Rhodiola (unspecified)
Rhodiola sacra
Reginin A
Rosarin
Rhodiola
Rauwolscine
Rhodiola crenulata
Robusta Coffee
Sceletium
Synephrine
Salt (sea)
salt
Salidrosides
salt (unspecified)
Sodium
Sodium
Schisandrins
Siberian ginseng
Schizandrol A
Sodium
Stabilizer
Schisandra
Schisandrin
Tyramine
Tissue (unspecified)
Tribulin
Theanine
Tyrosine alpha ketoglutarate
Tyrosine alpha-ketoglutaric acid
Tyrosine
Theacrine
Theanine
Tyrosine alpha-ketoglutarate
Undeca-2E, 7Z, 9E-Trienoic Acid Isobutylamide
Vitamin B5
Vitamin C (Ascorbate)
Vitamin B5 (calcium pantothenate)
Vitamin B5 (mixed)
Vitamin B
Withanolides
Withanolide
Waldelactone
Xanthine
Xanthine (unspecified)
yohimbine
Yohimbines (unspecified)
Zanthoxylum piperitum