Lou Gehrig's Disease

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Other names for Lou Gehrig's Disease

Amyotrophic lateral sclerosis (ALS)
Motor neuron disease (MND)
Progressive muscular atrophy
Spinal muscular atrophy (in differential diagnosis)

Synopsis of Lou Gehrig's Disease

Lou Gehrig’s Disease, medically known as amyotrophic lateral sclerosis (ALS), is a progressive neurodegenerative disease that affects motor neurons—the nerve cells in the brain and spinal cord that control voluntary muscle movement. As these neurons degenerate and die, the brain can no longer initiate or control muscle actions, leading to progressive paralysis.

ALS typically begins with muscle weakness in the limbs or speech and gradually affects the ability to move, speak, swallow, and eventually breathe. Cognitive function is generally preserved, though some patients may experience mild cognitive or behavioral changes.

Types of ALS:

  • Sporadic ALS (90–95%) – Occurs without a family history

  • Familial ALS (5–10%) – Inherited genetic mutations (e.g., SOD1, C9orf72)

Common early symptoms:

  • Muscle twitching (fasciculations)

  • Weakness in hands, feet, legs, or speech

  • Clumsiness or tripping

  • Difficulty holding objects

  • Slurred or nasal speech

  • Cramping or stiffness in muscles

Later-stage symptoms:

  • Progressive loss of mobility

  • Difficulty swallowing (dysphagia)

  • Breathing difficulties

  • Complete paralysis (while cognition remains intact)

When to see a doctor:
Any progressive muscle weakness, speech changes, or difficulty swallowing or breathing should be evaluated by a neurologist. Diagnosis typically involves clinical examination, EMG (electromyography), nerve conduction studies, and MRI to rule out other conditions.

Natural remedies for Lou Gehrig's Disease

Nutrient-Dense, High-Calorie Diet: To help prevent weight loss and support muscle function.

Speech and Physical Therapy: Preserves function and communication as long as possible.

Gentle Exercise and Range-of-Motion Work: Maintains flexibility and circulation.

Emotional and Mental Health Support: Counseling or support groups for coping.

Adaptive Equipment: Helps maintain independence with mobility and daily tasks.