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VitabaseHealth Conditions

Nausea and Vomiting

Other NamesAcute Nausea and Vomiting
Natural Remedies10
Ingredients86
Table of contents

Other Names

Acute Nausea and VomitingAirsicknessAnticipatory Nausea and VomitingBeing Sick to Your StomachBilious VomitingBreakthrough Nausea and VomitingCannabinoid Hyperemesis SyndromeCar SicknessChemotherapy-Induced Nausea and VomitingChronic Unexplained Nausea and VomitingCHSCINVCoffee-Ground VomitingCUNVCVSCyclic Vomiting SyndromeDelayed Nausea and VomitingDry HeavesEmesisFecal VomitingFunctional VomitingGastroparesis-Like SyndromeGLSHematemesisHyperemesis GravidarumKinetosisMal de MerMorning SicknessMotion SicknessN/VNaupathiaNauseaNausea or VomitingNauseousnessNon-productive EmesisPONVPost-Chemotherapy Nausea and VomitingPostoperative EmesisPostoperative NauseaPostoperative Nausea and VomitingPostoperative VomitingProjectile VomitingQualmQueasinessRadiation-Induced Nausea and VomitingRefractory Nausea and VomitingRetchingRINVSeasicknessSick to One's StomachSicknessSqueamishnessStomach UpsetUpset StomachVomitingVomiting of Unexplained EtiologyVomitusVUE

Synopsis

Nausea and Vomiting: A Nutrition and Natural-Health Reference

1. Definition and Clinical Presentation

Nausea is a subjective sensation of discomfort in the stomach that is frequently accompanied by the feeling of a need to vomit and is often described as a vague, queasy feeling that can be difficult to articulate. Vomiting, or emesis, is the forceful expulsion of the contents of the stomach through the mouth and is a complex reflex action involving multiple body systems.

Nausea frequently is relieved by vomiting and may be accompanied by increased parasympathetic nervous system activity including diaphoresis, salivation, bradycardia, pallor, and decreased respiratory rate. Retching ("dry heaves") is the simultaneous contraction of the abdominal muscles and muscles of inspiration that may occur with vomiting. Vomiting should be differentiated from regurgitation, the nonforceful expulsion of gastric contents into the esophagus, and eructation (belching), the expulsion of swallowed gastric air.

The act of emesis involves a sequence of events that can be divided into three phases: preejection, ejection, and postejection. The preejection phase includes the symptoms of nausea, along with salivation, swallowing, pallor, and tachycardia. The ejection phase comprises retching and vomiting. Retching is characterized by rhythmic, synchronous, inspiratory movements of the diaphragm and the abdominal and external intercostal muscles, while the mouth and the glottis are kept closed.

Nausea and vomiting are crucial protective defense mechanisms that help humans and other vomit-competent animals avoid ingesting or digesting potentially toxic substances. These processes serve as an immediate response to harmful agents, with nausea acting as an early warning signal and vomiting providing a means to expel harmful substances from the body.

2. Body Systems Involved

The underlying mechanisms involved in nausea are complex and encompass psychological states, the central nervous system, autonomic nervous system, gastric dysrhythmias, and the endocrine system.

Afferent information from various stimuli are relayed to the nucleus tractus solitarius via four pathways: vestibular and cerebellar, cerebral cortex and limbic system, area postrema, and the gastrointestinal tract via the vagus nerve. Once any of these neural pathways are activated, it culminates in the sensation of nausea with or without vomiting.

The chemoreceptor trigger zone at the base of the fourth ventricle has numerous dopamine D2 receptors, serotonin 5-HT3 receptors, opioid receptors, acetylcholine receptors, and receptors for substance P. Stimulation of different receptors are involved in different pathways leading to emesis; in the final common pathway, substance P appears to be involved.

The vestibular system, which sends information to the brain via cranial nerve VIII (vestibulocochlear nerve), plays a major role in motion sickness and is rich in muscarinic receptors and histamine H1 receptors. Cranial nerve X (the vagus nerve) is activated when the pharynx is irritated, leading to a gag reflex. Vagal and enteric nervous system inputs transmit information regarding the state of the gastrointestinal system, and irritation of the GI mucosa by chemotherapy, radiation, distention, or acute infectious gastroenteritis activates the 5-HT3 receptors of these inputs.

In the gastrointestinal tract, enterochromaffin cells synthesize more than 90% of the body's 5-hydroxytryptamine (serotonin, 5-HT), as well as large amounts of substance P (SP), which are both fundamental to gastrointestinal motility, nausea, and vomiting.

Severe vomiting can lead to symptomatic dehydration and electrolyte abnormalities (typically a metabolic alkalosis with hypokalemia) or rarely to an esophageal tear, either partial (Mallory-Weiss) or complete (Boerhaave syndrome). Chronic vomiting can result in undernutrition, weight loss, and metabolic abnormalities.

3. Contributing and Associated Factors

3.1 Gastrointestinal Causes

Nausea and vomiting are nonspecific symptoms that occur with a wide variety of metabolic, toxic, inflammatory, and structural disorders. Determination of cause requires careful assessment of symptoms associated with the episode, in particular, duration, relation to meals, precipitating factors, and contents of the vomitus.

Gastrointestinal etiologies include obstruction, functional disorders, and organic diseases. Abrupt onset of nausea or vomiting is usually due to a toxic, infectious, or central nervous system disorder. Acute symptoms lasting for several hours to a few days are found with inflammatory or structural lesions. Chronic symptoms, particularly if they are intermittent, frequently are produced by an obstructive or inflammatory process within the gastrointestinal tract.

3.2 Central Nervous System and Endocrine Causes

Central nervous system etiologies are primarily related to conditions that increase intracranial pressure, and typically cause other neurologic signs. Pregnancy is the most common endocrinologic cause of nausea and must be considered in any woman of childbearing age. Numerous metabolic abnormalities and psychiatric diagnoses also may cause nausea and vomiting.

3.3 Pregnancy-Related Nausea and Vomiting

Nausea and vomiting of pregnancy (NVP) is a common condition that affects up to 70% of pregnant women. Hyperemesis gravidarum (HG) is considered the serious form of NVP, which is reported in 0.3–10.8% of pregnant women. The exact cause of nausea and vomiting during pregnancy is not known; however, it is believed to be caused by a rapidly rising blood level of a hormone called human chorionic gonadotropin (HCG), which is released by the placenta.

Individuals with a personal or family history of hyperemesis gravidarum, motion sickness, or migraine-associated nausea are at greater risk, suggesting a shared biological susceptibility.

3.4 Psychological and Stress Factors

Pregnant women with psychological disorders are inclined to be exposed to adverse health outcomes, including NVP and HG. So far, 17 studies suggest that adverse psychological factors are associated with HG or NVP. Possible adverse psychological factors include depression, anxiety, mood disorders, and stress. In a structured clinical interview, patients with HG had a higher prevalence of mood or anxiety disorders before pregnancy compared with women without HG (32.7% vs. 10.0%).

While psychological conditions such as depression and anxiety often coexist with hyperemesis gravidarum, these may be more likely sequelae of the illness rather than contributing causes. In a recent study, approximately 57.4% of patients with hyperemesis gravidarum also had a diagnosis of depression or anxiety.

3.5 Sleep Disruption

Research indicates that severe NVP increases the risk of insomnia among early pregnant women. One case-control study found that, compared with a healthy control group (7.7%), women diagnosed with hyperemesis gravidarum were more likely to report poor sleep quality (60.9%).

3.6 Dietary Patterns

Rates of nausea and vomiting in pregnancy were correlated with high intake of macronutrients (kilocalories, protein, fat, carbohydrate), as well as sugars, stimulants, meat, milk and eggs, and with low intake of cereals and pulses. Factor analysis of dietary components revealed one factor significantly associated with NVP rate, which was characterized by low cereal consumption and high intake of sugars, oilcrops, alcohol, and meat. These results provide further evidence for an association between diet and NVP prevalence across populations.

4. Nutrients, Herbs, and Natural Ingredients

4.1 Ginger (Zingiber officinale)

Traditional Use

Ginger has been used for thousands of years in Asian and Ayurvedic medicine as an anti-inflammatory and anti-pyretic agent and to treat indigestion, nausea, stomachache, and numerous other ailments. References to ginger as a medicine and as a spice appear in ancient Chinese and Sanskrit writings, and in surviving Persian, Arabic, Greek, and Roman texts. Medieval writings from many European countries indicate that ginger was a standard ingredient in recipes for the kitchen and the apothecary.

It has been used in traditional Chinese and Indian medicine (Ayurveda) for over 25 centuries as a digestive aid and anti-nausea remedy, as well as for treating bleeding disorders and respiratory conditions. In Traditional Chinese Medicine, ginger is known as Sheng Jiang and is valued for its ability to dispel cold and dampness from the body, and is often used to treat symptoms such as chills, nausea, and digestive discomfort. The classical Ayurvedic text Charaka Samhita (written approximately 300 BCE) refers to ginger as "vishwabhesaj" — the universal medicine — reflecting its extraordinarily broad range of therapeutic applications.

Proposed Mechanisms

Ginger (via its active constituents gingerols and shogaols) acts via 5-hydroxytryptamine 3 (5-HT₃) receptor antagonism and substance P/neurokinin-1 (NK-1) inhibition.

Scientific Evidence

A systematic review of evidence from randomized controlled trials assessed the efficacy of ginger for nausea and vomiting. Six studies met all inclusion criteria. Three on postoperative nausea and vomiting were identified; two of these suggested that ginger was superior to placebo and equally effective as metoclopramide. However, the pooled absolute risk reduction for the incidence of postoperative nausea indicated a non-significant difference between the ginger and placebo groups for ginger 1 g taken before operation. One study was found for each of the following conditions: seasickness, morning sickness, and chemotherapy-induced nausea, and these studies collectively favoured ginger over placebo.

The authors of that review reported that ginger was found to be a promising antiemetic herbal remedy, but that the clinical data were insufficient to draw firm conclusions.

A subsequent systematic review and meta-analysis of ginger for nausea and vomiting in pregnancy included twelve RCTs involving 1,278 pregnant women. A separate meta-analysis of postoperative outcomes pooled fourteen randomized trials with a total of 1,506 patients and found that at different time points, the control group had higher postoperative nausea scores than the experimental group, with statistically significant differences.

Evidence strength: Moderate for pregnancy-related nausea and vomiting; mixed and methodologically limited for postoperative and chemotherapy-induced nausea. Evidence bases are restricted by heterogeneous preparations, dose variations, and small sample sizes across trials.

4.2 Vitamin B6 (Pyridoxine)

Traditional and Historical Use

Pyridoxine primarily treats vitamin B6 deficiency and helps alleviate nausea and vomiting during pregnancy. Its use for pregnancy-related nausea has been documented in clinical practice for many decades and is reflected in regulatory endorsement by major obstetric bodies.

Proposed Mechanisms

The pyridoxine mechanism of affecting nausea is unknown. As a cofactor for more than 140 enzymes, pyridoxal 5'-phosphate (PLP) is involved in immune regulation, neurotransmission, and lipid and amino acid metabolism, and is recognized as the most sensitive biomarker of vitamin B6 status in humans.

Scientific Evidence

In two randomized, placebo-controlled trials, 30–75 mg of oral pyridoxine per day significantly decreased nausea in pregnant women who were experiencing nausea. However, the authors of a Cochrane Review of studies on interventions for nausea and vomiting in pregnancy could not draw firm conclusions on the value of vitamin B6 to control the symptoms of morning sickness.

Randomized trials have shown that a combination of vitamin B6 and doxylamine (an antihistamine) is associated with a 70% reduction in nausea and vomiting in pregnant women and lower hospitalization rates for this problem. The American College of Obstetrics and Gynecology (ACOG) recommends monotherapy with 10–25 mg of vitamin B6 three or four times a day to treat nausea and vomiting in pregnancy, adding doxylamine if the patient's condition does not improve.

One clinical trial found that women experiencing nausea and/or vomiting in pregnancy had significantly lower levels of circulating vitamin B6 (P=0.007) compared with those without this symptom.

A 2023 systematic review and meta-analysis identified 18 eligible studies from 548 initially screened articles; eight studies showed beneficial effects with pyridoxine alone as the supplementation.

Research has found conflicting results regarding using vitamin B6 supplements in treating morning sickness, gestational diabetes, premenstrual syndrome, and certain other conditions.

Evidence strength: Moderate for pregnancy-related nausea. Evidence for the combination product (vitamin B6 + doxylamine) is stronger than for pyridoxine alone. The precise mechanism by which B6 reduces nausea remains unexplained.

4.3 Peppermint (Mentha × piperita)

Traditional Use

Peppermint has a long history of use in Western herbal traditions and folk medicine as a remedy for digestive discomfort, including nausea. It has been consumed as an infusion and applied as an essential oil in European botanical medicine for centuries.

Proposed Mechanisms

The inhalation of peppermint essential oil may alleviate nausea and vomiting through several mechanisms. Peppermint oil has been shown to block serotonin receptors in the gastrointestinal tract that trigger the nausea and vomiting reflex. The active compounds of peppermint oil are menthol (35–45%) and menthone (10–30%), which exhibit antispasmodic effects. These compounds help relax the smooth muscles of the gastrointestinal tract.

Scientific Evidence

Several randomised controlled trials have been conducted to evaluate the effect of peppermint on postoperative nausea and vomiting, nausea and vomiting in pregnancy, and chemotherapy-induced nausea and vomiting; however, its clinical efficacy has not been established yet. Preliminary studies suggest peppermint oil may be able to reduce postoperative nausea.

Evidence strength: Preliminary. The available RCTs are small, heterogeneous in design, and insufficient to establish efficacy. Aromatherapy with peppermint essential oil is considered a low-risk adjunct in some clinical settings but lacks the rigorous evidence base of ginger or vitamin B6.

4.4 Cannabinoids (Cannabis-Derived Compounds)

Traditional Use

Cannabis has long been known to limit or prevent nausea and vomiting from a variety of causes. Cannabis has a long history of medicinal use.

Proposed Mechanisms

Considerable evidence demonstrates that manipulation of the endocannabinoid system regulates nausea and vomiting in humans and other animals. The anti-nausea/anti-emetic effects of CBD may be mediated by indirect activation of somatodendritic 5-HT1A receptors in the dorsal raphe nucleus; activation of these autoreceptors reduces the release of 5-HT in terminal forebrain regions.

Scientific Evidence

In vitro and in vivo evidence has been reviewed for the effectiveness of the nonpsychoactive cannabinoid CBD in managing nausea and vomiting, including its acidic precursor cannabidiolic acid (CBDA) and a methylated version (CBDA-ME). CBD has demonstrated efficacy in reducing nausea and vomiting in these preclinical models, with CBDA and CBDA-ME being more potent. The data suggest a need for these compounds to be evaluated in clinical trials.

Cannabinoids may be a useful therapeutic option for people with chemotherapy-induced nausea and vomiting that respond poorly to commonly used anti-emetic agents. However, unpleasant adverse effects may limit their widespread use. There are no reports of any specific evaluation of CBD alone to reduce nausea and vomiting in human chemotherapy patients.

Evidence strength: Preclinical evidence (animal models, in vitro) is substantial. Human clinical trial evidence for CBD alone is lacking. Synthetic THC formulations (dronabinol, nabilone) have regulatory approval in several jurisdictions specifically for chemotherapy-induced nausea and vomiting, but these are pharmaceutical compounds rather than natural preparations.

4.5 Chamomile (Matricaria chamomilla)

Traditional Use

Chamomile has been used widely in European herbal traditions as a digestive and antispasmodic remedy, consumed as an infusion for stomach upset, nausea, and gastrointestinal cramps. It appears in the German Commission E and ESCOP monograph literature as a recognized herbal medicine for gastrointestinal spasm and inflammatory conditions of the GI tract.

Proposed Mechanisms and Evidence

Chamomile contains apigenin, which has antispasmodic and anxiolytic effects. Rigorous human clinical trial evidence specifically for chamomile's anti-nausea effects is limited; the published evidence base is largely from traditional use documentation and in vitro or animal studies.

Evidence strength: Very preliminary for nausea specifically. Chamomile is recognized in phytomedicine for gastrointestinal spasm, but targeted clinical evidence for nausea and vomiting is lacking.

4.6 Other Botanical Ingredients Studied in the Context of Chemotherapy-Induced Nausea

Turmeric (curcumin) acts on neurotransmitter systems and offers potent anti-inflammatory and antioxidant effects. Plants such as Pinellia ternata, lemon, fennel, and licorice show varied mechanisms including gastrointestinal regulation, anti-inflammatory activity, and neurotransmitter modulation. These findings are derived predominantly from preclinical or early-phase research, and robust human clinical trial evidence is absent for most of these agents in the context of nausea and vomiting specifically.

4.7 Acupressure and Acupuncture at Point PC6 (Neiguan)

Traditional Use

Acupuncture and acupressure are traditional Chinese remedies for nausea and vomiting. During acupuncture, a therapist inserts thin needles into specific points on the body, while acupressure aims to stimulate the same points using pressure instead of needles. Both techniques stimulate nerve fibers, which transmit signals to the brain and spinal cord, and some believe these signals can decrease nausea.

Scientific Evidence

There is evidence that acupuncture may help relieve nausea and vomiting associated with cancer treatment. Acupressure reduces the severity of acute and delayed nausea; however, it has no benefit on the incidence and severity of vomiting.

Acupressure and acupuncture, particularly targeting the P6 point on the forearm, have shown mixed results, with some studies suggesting benefits for different types of nausea, including that induced by anesthesia. In at least one study on pregnancy nausea, women in all treatment groups (including the fake acupuncture group) showed significant improvements in nausea and dry retching compared to the no-treatment group; however, neither form of real acupuncture proved markedly more effective than fake acupuncture.

Evidence strength: Mixed. Some systematic reviews support benefit for specific contexts (chemotherapy-induced nausea, postoperative nausea), but distinguishing true effects from placebo effects via sham acupuncture comparisons remains methodologically challenging.

5. Dietary and Lifestyle Factors

5.1 Meal Composition and Frequency

The best foods for nausea and vomiting are typically bland, low-fat, and easy to digest. The BRAT diet (Bananas, Rice, Applesauce, Toast) is a classic choice due to its gentle nature and ability to help bind stools. Prioritizing small, frequent meals rather than large ones helps prevent overwhelming the stomach.

Fatty, spicy, acidic, and highly sugary foods should be avoided, as these can exacerbate nausea and vomiting. These recommendations are consistent across clinical and nutritional guidance, though formal RCT evidence for specific meal patterns in nausea management is limited.

5.2 The BRAT Diet

The BRAT diet stands for bananas, rice, applesauce, and toast. Because this diet is low in nutrients, it is not meant to be followed long term. This diet recommends certain bland, starchy foods that may help when dealing with nausea, diarrhea, or an upset stomach. The BRAT diet was formerly recommended for children recovering from stomach upset, but the American Academy of Pediatrics now recommends that children resume a normal diet within 24 hours of becoming sick. The BRAT diet was often recommended for nausea, vomiting and diarrhea but is no longer formally recommended because of how restrictive it is.

5.3 Hydration

Maintaining adequate hydration by sipping clear fluids slowly — such as water, electrolyte solutions, or clear broths — is crucial for managing vomiting. Experts agree that it is not advisable for people who are actively vomiting to eat solid foods; they recommend sipping clear liquids instead. Foods from the BRAT diet may be incorporated once vomiting has stopped.

5.4 Dietary Patterns in Pregnancy-Related Nausea

Rates of nausea and vomiting in pregnancy were correlated with high intake of macronutrients (kilocalories, protein, fat, carbohydrate), as well as sugars, stimulants, meat, milk and eggs, and with low intake of cereals and pulses. High fat, spicy, or gaseous foods are not well tolerated. Citrus fruits and drinks are often considered to have too much acid for women experiencing nausea in pregnancy.

Lifestyle changes, such as eating smaller, more frequent meals and opting for bland foods, can help manage symptoms.

5.5 Psychological and Behavioral Factors

Nausea and vomiting of pregnancy have been reported to be associated with distinct physiological responses to psychosocial stress. The severity of complaints might vary from one pregnant woman to another and even between pregnancies of the same woman, which suggests the contribution of genetic, biological, and psychological factors.

NVP can lead to a range of other mental and physical health problems, such as fatigue, anxiety, and depression, thereby reducing overall quality of life. Sleep quality typically decreases during pregnancy.

5.6 Aromatherapy as a Lifestyle Adjunct

Inhalation and massage aromatherapy are used as adjuncts for chemotherapy-induced nausea and retching. Peppermint essential oil may be helpful for nausea; patients may carry a bottle and sniff it throughout the day when needed. Alternative therapies for nausea are needed that may be more effective with fewer side effects, and aromatherapy — which involves inhaling essential oils — is considered a mild therapeutic modality without severe side effects.

References

Natural Remedies

Remedy 1
Ginger Tea or Chews: Ginger contains active compounds gingerol and shogaol, which calm the stomach and have well-established anti-nausea properties rooted in over 2,000 years of traditional medicine use. Brew fresh ginger slices in hot water for a soothing tea, chew on raw ginger or ginger candy, or stir grated ginger into a warm broth.
Remedy 2
Peppermint Aromatherapy or Tea: Peppermint contains menthol, which has a soothing effect on stomach muscles and can help calm the digestive system and ease the urge to vomit. Sip peppermint tea slowly, inhale peppermint essential oil directly from the bottle, or apply a diluted drop to the back of the neck for fast-acting relief.
Remedy 3
P6 Acupressure (Neiguan Point): Acupressure at the P6 point on the inner wrist is a traditional Chinese medicine technique with clinical evidence supporting its ability to reduce nausea. Place your thumb approximately two to three finger-widths below the inner wrist crease between the two central tendons and apply firm, circular pressure for two to three minutes on each wrist, or wear acupressure wristbands for continuous relief.
Remedy 4
BRAT Diet and Bland Foods: Heavy, greasy, or spicy foods can worsen nausea, while bland, easily digestible options — bananas, rice, applesauce, and toast — are far better tolerated by a sensitive stomach. Eat small amounts slowly and frequently rather than large meals, which can overwhelm the digestive system and intensify symptoms.
Remedy 5
Controlled Deep Breathing: Slow, diaphragmatic breathing engages the parasympathetic nervous system, calming both the mind and digestive tract and reducing stress-triggered nausea. Inhale through your nose for four counts, hold for four counts, then exhale slowly through your mouth for four counts, and repeat five to ten times until the sensation subsides.
Remedy 6
Lemon Aromatherapy or Lemon Water: The citrus scent of fresh lemon has been shown to help reduce nausea, particularly pregnancy-related morning sickness, by releasing calming essential oils. Slice a fresh lemon and inhale its fragrance, squeeze fresh lemon juice into warm water and sip slowly, or carry a small vial of lemon essential oil for on-the-go relief.
Remedy 7
Hydration with Electrolyte-Rich Fluids: Vomiting depletes fluids and electrolytes, and dehydration itself can worsen nausea, creating a difficult cycle. Sip small, frequent amounts of water, clear herbal teas, coconut water, or diluted electrolyte drinks throughout the day — never large amounts at once, which can overwhelm an already irritated stomach.
Remedy 8
Chamomile Tea: Chamomile has long been valued in herbal tradition as a digestive relaxant with gentle anti-inflammatory properties, and it can help calm gastrointestinal disturbances that contribute to nausea. Steep dried chamomile flowers in hot water for several minutes, then sip the warm tea slowly to ease stomach discomfort and promote relaxation.
Remedy 9
Fennel Seeds: Fennel seeds have been used traditionally to address digestive upset including nausea and bloating, and are a simple kitchen-cabinet remedy. Chew on a small teaspoon of fennel seeds directly, or steep them in hot water for five minutes to make a mild, stomach-settling tea.
Remedy 10
Rest, Posture, and Odor Avoidance: Staying upright after eating (avoiding lying down immediately) helps prevent gastric contents from pressing against the stomach opening, while avoiding strong odors — perfumes, cooking smells, or smoke — can prevent sensory triggers from worsening nausea. Rest in a cool, well-ventilated space, get fresh air when possible, and avoid sudden movements which can amplify the sensation.

Ingredients

These ingredients are often used in alternative medicine to support nausea and vomiting.
  • artichokeScientific

    Artichoke leaf extract has been shown in multiple clinical studies to reduce nausea as part of the functional dyspepsia symptom complex. ESCOP monographs list nausea and vomiting as indications. Post-marketing surveillance studies with 320–640 mg ALE three times daily found nausea resolved among the majority of patients at 2 months.

  • cannabis sativa oilScientific

    Cannabinoids from Cannabis sativa modulate the endocannabinoid system via CB1 receptor agonism to suppress nausea and vomiting. A PMC review (PMC3165951) confirms considerable evidence that endocannabinoid system manipulation regulates nausea and vomiting in humans. Cannabis-based medicines have been found effective antiemetics in clinical trials, particularly for chemotherapy-induced nausea and vomiting. Cannabidiol (CBD) specifically suppresses nausea and vomiting via indirect 5-HT1A autoreceptor activation.

  • cardamomScientific

    Cardamom (Elettaria cardamomum) has been identified in multiple peer-reviewed studies as an antiemetic. Its antispasmodic properties relax GI smooth muscle, reducing nausea and vomiting. Clinical studies have demonstrated that cardamom essential oil aromatherapy significantly reduces intra- and postoperative nausea and vomiting, and it has been tested as part of validated PONV aromatherapy blends in Cochrane-reviewed trials.

  • chamomileScientific

    Chamomile (Matricaria chamomilla) is documented in traditional medicine globally for nausea, vomiting, and GI upset. Its active constituent apigenin has antispasmodic and anxiolytic properties relevant to nausea pathways. A 2025 triple-blind randomized study (PMC11910166) investigated chamomile's effectiveness in reducing nausea and vomiting after middle ear surgery, and multiple herbal reviews (Biomedical Research and Therapy, 2018) identify chamomile among the principal antiemetic medicinal plants.

  • chen piScientific

    Chen Pi has been used for millennia in TCM as an antiemetic. Its volatile oils and flavonoids (hesperidin, nobiletin) are documented to stimulate gastric secretions and modulate gastrointestinal motility. Pharmacopeial listing in China (Pharmacopoeia of the People's Republic of China) reflects extensive clinical tradition backed by mechanistic research.

  • cinnamonScientific

    Cinnamon (Cinnamomum species) has traditional and emerging clinical evidence as an antiemetic. A RCT demonstrated that ginger and cinnamon aromatherapy reduced nausea and vomiting after chemotherapy in cancer patients (Amin et al., 2022, cited in PMC11881962). A cinnamon oral formulation study found reduction of nausea, vomiting, and menstrual pain in college students (Jaafarpour et al., 2015). Cinnamon shares antispasmodic properties with ginger and is listed among traditional antiemetic plants.

  • diamine oxidaseScientific

    Nausea and vomiting are recognized gastrointestinal manifestations of histamine intolerance related to DAO deficiency. Clinical classification of HIT symptoms includes vomiting, and DAO supplementation trials report improvements in GI symptom composites that include nausea. Histamine acts on gut H1/H2 receptors and the vomiting center to trigger these symptoms.

  • fennelScientific

    Fennel (Foeniculum vulgare) has traditional use and emerging clinical evidence as an antiemetic. Its essential oil constituents anethole and fenchone relax GI smooth muscle via calcium channel inhibition, reducing nausea-associated GI spasm. The Biomedical Research and Therapy review (2018) identifies fennel among key traditional antiemetic plants, and a PMC 2025 systematic review documents antiemetic mechanisms for fennel in CINV.

  • ferula assafoetidaScientific

    In the RCT on functional dyspepsia (PMC6129344), the Asafin formulation produced 75% improvement in motion sickness (nausea) scores in the treatment group versus less than 10% in placebo. Traditional use also includes nausea associated with indigestion.

  • gingerScientific

    Ginger (Zingiber officinale) is one of the most extensively studied natural antiemetics. Multiple systematic reviews and meta-analyses of RCTs confirm efficacy for nausea and vomiting of pregnancy (NVP), chemotherapy-induced nausea and vomiting (CINV), and postoperative nausea and vomiting. The active constituents gingerols and shogaols act via 5-HT3 receptor antagonism and NK-1 inhibition.

  • glucoamylaseScientific

    Clinical evidence from a trial in hospitalized patients found that enzyme preparations containing glucoamylase improved symptoms including nausea and vomiting. These effects are attributed to improved overall upper GI digestive function rather than a direct anti-emetic mechanism.

  • lavenderScientific

    A double-blind RCT found that lavender aromatherapy significantly relieved nausea and vomiting as components of primary dysmenorrhea symptomatology. Lavender has been investigated in clinical trials for postoperative nausea as an aromatherapy intervention. Evidence is modest and primarily as an adjunct rather than standalone antiemetic.

  • lemonScientific

    Lemon aromatherapy has been investigated in RCTs for nausea and vomiting of pregnancy (NVP). A double-blind RCT (PMC4005434) found lemon inhalation aromatherapy significantly reduced NVP severity. A combined peppermint-lemon inhalation RCT (PubMed 33344211) also confirmed efficacy for mild-to-moderate NVP, and a pediatric RCT found peppermint-lemon aromatherapy effective for chemotherapy-induced nausea and vomiting in children.

  • menthol oilScientific

    Menthol, as a primary constituent of peppermint oil, has been studied in randomized controlled trials for postoperative and chemotherapy-induced nausea and vomiting. The mechanism involves 5-HT3 receptor antagonism and smooth muscle antispasmodic activity.

  • mintScientific

    Peppermint oil inhalation and oral extract have been tested in RCTs for postoperative, chemotherapy-induced, and pregnancy-related nausea. Evidence shows statistically significant reductions in nausea severity, though effect sizes are modest and evidence certainty is rated low due to blinding difficulties and small samples.

  • peppermintScientific

    Peppermint (Mentha × piperita), primarily via inhalation aromatherapy or oral extract, has clinical evidence supporting reduction of nausea and vomiting in postoperative, pregnancy, and chemotherapy settings. A Cochrane-included systematic review and meta-analysis (2025, PMC12294836) found peppermint oil inhalation may reduce severity of nausea and vomiting, though evidence certainty is low. An RCT in breast cancer chemotherapy patients showed significantly lower nausea/vomiting scores at 24 and 48 hours post-intervention (PubMed 33118401).

  • pinellia ternataScientific

    Pinellia ternata (Banxia) is a foundational antiemetic herb in traditional Chinese medicine, used since the Han Dynasty for nausea and vomiting. A systematic review and meta-analysis of 22 RCTs (n=1,787 patients; Phytomedicine 2023) found Pinellia ternata-containing TCM combined with 5-HT3 receptor antagonists significantly outperformed 5-HT3RAs alone for CINV. Pharmacological studies confirm it contains components that inhibit the emetic response.

  • saccharomyces boulardiiScientific

    Meta-analyses of S. boulardii as adjuvant to H. pylori eradication therapy show a statistically significant reduction in nausea (RR≈0.50), but not vomiting specifically. In pediatric gastroenteritis, S. boulardii reduces vomiting duration as part of its broader anti-gastroenteritis effect. Evidence is strongest for nausea as a side-effect of antibiotic regimens.

  • spearmint leafScientific

    Spearmint (Mentha spicata) has been studied in aromatherapy blends and in oral form for nausea and vomiting, including PONV and CINV. It is included in Cochrane-reviewed aromatherapy blends for PONV and a PMC 2025 systematic review documents its antiemetic mechanisms via GI smooth muscle relaxation. A double-blind RCT found spearmint essential oil capsules significantly reduced the intensity and frequency of chemotherapy-induced nausea and vomiting.

  • vitamin B1Scientific

    Gastrointestinal beriberi—thiamine deficiency primarily affecting the digestive system—presents with nausea, vomiting, and abdominal pain that resolves with thiamine repletion. Thiamine supplementation has been shown to improve nausea and GI motility disorders. FDA-approved parenteral thiamine is indicated in patients who cannot take oral supplementation due to severe nausea and vomiting.

  • vitamin B6Scientific

    Vitamin B6 (pyridoxine) is a first-line pharmacological treatment for nausea and vomiting of pregnancy (NVP). The NIH Office of Dietary Supplements confirms that in two RCTs, 30–75 mg/day oral pyridoxine significantly decreased nausea in pregnant women. ACOG recommends 10–25 mg three to four times daily as monotherapy first-line therapy for NVP.

  • abies spectabilisTraditional

    Vomiting is listed among the traditional indications for A. spectabilis in Himalayan ethnobotany. The plant's carminative and antispasmodic properties documented in traditional sources provide plausibility for this use.

  • ajwainTraditional

    Ajwain is used traditionally in Ayurvedic and South Asian folk medicine for nausea, particularly related to indigestion and motion sickness. Its carminative and digestive properties are the proposed mechanism. No human clinical trials for nausea or vomiting have been conducted.

  • allspiceTraditional

    Allspice is documented in traditional herbalism as a remedy for nausea and vomiting, particularly associated with digestive upset. Its carminative, aromatic, and digestive-stimulant properties are attributed to eugenol and related volatile oils. No human clinical evidence exists.

  • alpinia galangalTraditional

    Galangal root is widely used in TCM and Ayurveda as an antiemetic, prescribed for nausea, vomiting, and hiccups. Pharmacological reviews confirm antiemetic activity in preclinical studies. No dedicated human RCTs for nausea have been published specifically for A. galanga.

  • aniseTraditional

    Anise (Pimpinella anisum) has longstanding traditional use in multiple medicine systems for nausea, vomiting, and GI spasm. A Biomedical Research and Therapy review (2018) lists anise among the key traditional antiemetic medicinal plants. Anise oil demonstrates significant antispasmodic effects by relaxing methacholine-induced GI smooth muscle contractions, potentially via potassium channel activation—a plausible antiemetic mechanism.

  • atractylodesTraditional

    Atractylodes macrocephala has been used in TCM formulas for nausea, vomiting, and chronic gastritis for centuries. Sesquiterpenoids from the herb have demonstrated antiemetic activity in preclinical studies. No modern randomised human trials specifically investigating atractylodes for nausea or vomiting have been published.

  • bananaTraditional

    Banana is a traditional component of the BRAT diet (Banana, Rice, Applesauce, Toast) used for nausea, vomiting, and gastrointestinal upset across many cultures. Its bland, easily digestible carbohydrate content and mild astringency make it a widely recommended food during episodes of nausea. Documented traditional and clinical dietary use exists, but controlled trials for nausea specifically are absent.

  • barberryTraditional

    Barberry is documented in traditional and herbal medicine references as a remedy for nausea, listed alongside other digestive indications. No clinical trial data exist specifically for barberry in nausea or vomiting.

  • basilTraditional

    Basil is used in Ayurveda, TCM, and folk medicine for nausea and vomiting, often as leaf tea. Ethnobotanical records consistently document this use. The carminative and antispasmodic properties of volatile oils (linalool, eugenol) provide pharmacological plausibility, though no human clinical trials exist.

  • bayberryTraditional

    Bayberry is listed in traditional herbal medicine for nausea, and in large doses historically used to induce vomiting as a treatment for poisoning. WebMD and RxList document these traditional uses. No clinical trial evidence exists.

  • benegut perillaTraditional

    In Traditional Chinese Medicine (TCM), Perilla leaf (Zi Su Ye) has been incorporated into formulas designed to harmonize the stomach and alleviate nausea, vomiting, and morning sickness, with documented use spanning centuries. The clinical trials on Benegut assessed nausea as a secondary symptom endpoint but were not designed to specifically validate anti-emetic effects.

  • black pepperTraditional

    Black pepper is used in various traditional medicine systems including Ayurveda for nausea and vomiting, often combined with ginger. Its antiemetic use is documented in traditional contexts, though scientific human trial evidence specifically for this indication is absent.

  • cajuputTraditional

    Cajuput is documented in traditional Southeast Asian medicine as a carminative and stomach remedy, and its use for gastrointestinal discomfort including nausea is recorded in Malay traditional medicine. The presence of 1,8-cineole with smooth-muscle relaxant properties provides a pharmacological basis. No clinical trials exist.

  • camphor oilTraditional

    Camphor has been used in traditional medicine systems for digestive complaints including nausea, and is referenced in historical pharmacological texts for stimulant effects on the gastrointestinal system. No modern clinical trials exist for camphor oil as an antiemetic.

  • carawayTraditional

    Caraway has traditional use across multiple herbal systems for nausea, stomach aches, and general digestive upset. Its antispasmodic properties targeting intestinal smooth muscle are the proposed basis. No dedicated human clinical trials for nausea or vomiting specifically have been identified.

  • cassia barkTraditional

    Cassia bark is documented in traditional Chinese medicine and Ayurvedic medicine as a remedy for nausea, vomiting, and stomach spasms. RxList and other authoritative databases list nausea and vomiting prevention among its traditional oral uses. No clinical trials specifically examining these endpoints were identified in the peer-reviewed literature.

  • cayenne pepperTraditional

    Traditional herbal medicine documents cayenne's use for nausea, and the PMC review of Capsicum annuum lists postoperative nausea and vomiting among the conditions for which capsaicin has been used. Nausea is also a potential side effect of excessive cayenne intake, creating a complex, dose-dependent relationship.

  • cloveTraditional

    Clove and eugenol are traditionally used in Ayurvedic and Chinese medicine as antiemetics. Pharmacological reviews (PMC) document antiemetic and nausea-controlling properties of eugenol essential oil from clove.

  • coptis chinensisTraditional

    TCM texts and classical Chinese medicine monographs consistently list vomiting among the primary indications of Coptis chinensis, especially for 'heat in the stomach.' Berberine from the herb has been used internally for nausea and vomiting for over 2,000 years. No controlled human trials exist for this specific indication.

  • cuminTraditional

    Cumin has been used in Ayurvedic tradition for nausea, morning sickness, and colic. It is listed in traditional ethnobotanical records for these indications across multiple cultures. No controlled human trials specifically for nausea have been published.

  • dioscoreaTraditional

    Wild yam has a traditional history of use for nausea, particularly pregnancy-related nausea, documented in North American folk medicine since the 18th century. Some herbalists reference its antispasmodic and digestive properties as relevant. No clinical evidence exists.

  • feverfewTraditional

    Feverfew has been traditionally used to alleviate nausea and vomiting, including as a migraine-associated symptom. The PMC systematic review and NCCIH both cite nausea and vomiting among traditional applications. Clinical data specific to this indication are absent.

  • flowering quinceTraditional

    Emesis (vomiting) is one of the four classically documented indications for C. speciosa (Mugua) in TCM, cited in multiple peer-reviewed ethnobotanical and pharmacological reviews. The anti-emetic action is attributed to the herb's antispasmodic and stomach-harmonizing properties. No clinical trials for this specific indication are documented in indexed literature.

  • forsythiaTraditional

    Nausea and vomiting are listed among the traditional indications for Forsythia in Chinese medicine, and it is described as having antiemetic properties in pharmacological reviews. Animal models using free radical-induced emesis have been used to screen its antiemetic compounds. Clinical human evidence is absent.

  • fu lingTraditional

    The inner layer of Poria cocos (Fu Ling) is traditionally used for nausea, emesis, and gastric atony in TCM and Japanese Kampo medicine. Classical indications recorded in the Chinese Pharmacopoeia and historical texts document its use for these gastrointestinal symptoms. Scientific evidence for this specific endpoint is absent.

  • gardenia jasminoidesTraditional

    Fructus Gardeniae is documented in TCM for 'eliminating vexation' and treating stomach upset and nausea associated with heat conditions. It is included in TCM formulas such as Zhi-zi-chi decoction for vomiting and restlessness. Preclinical evidence for gastric motility or anti-emetic effects is limited; no human clinical trials specifically address nausea/vomiting.

  • gentianTraditional

    Gentiana species have been employed traditionally across Siberian, European, and Chinese medical traditions for nausea and vomiting as part of their broader gastrointestinal use. The 2025 PMC Gentianaceae review lists vomiting among traditional gastrointestinal indications. No human clinical trials specifically for nausea/vomiting have been identified.

  • gentian rootTraditional

    Gentian root has a longstanding traditional use for nausea and vomiting as part of its role as a bitter digestive tonic. Commission E and ESCOP list nausea among the dyspeptic complaints addressed by gentian. An open clinical study of 205 dyspeptic patients treated with gentian dry extract showed improvement in nausea and vomiting among other symptoms. No specific RCT for nausea/vomiting exists.

  • geraniumTraditional

    Traditional African and multi-cultural herbal medicine systems document geranium use for nausea and vomiting. The plant is listed as 'stomachic' and antispasmodic in traditional pharmacopoeias. No clinical trial evidence is available.

  • green chirettaTraditional

    Green chiretta is recorded in Ayurvedic and TCM traditions as a treatment for nausea, biliousness, and stomach upset, particularly when associated with fever or digestive infection. Its bitter stomachic action and anti-inflammatory properties provide a plausible basis. No dedicated clinical trials on nausea were identified.

  • hedychium spicatumTraditional

    Nausea and vomiting are among the most consistently cited traditional indications for H. spicatum rhizome across Ayurvedic, Unani, and folk systems. Multiple systematic reviews document this use. No controlled preclinical antiemetic studies or human clinical trials specifically evaluating this indication have been identified in indexed literature.

  • hyacinth beanTraditional

    Traditional Chinese Medicine (TCM) prescribes Lablab Semen Album specifically for vomiting, categorizing it as a herb that harmonizes the middle jiao and relieves summer-heat-induced nausea and vomiting. This indication is documented in multiple TCM pharmacopeias and ancient materia medica.

  • hyssopTraditional

    Hyssop is traditionally used as a stomachic and carminative for digestive upset including nausea, stomach pain, and intestinal gas. Its smooth-muscle-relaxing and aromatic properties are considered to underlie this use in Iranian and European herbal tradition.

  • indian baelTraditional

    Traditional Indian medicine systems (Ayurveda, Siddha, Unani) document the use of bael preparations for nausea and vomiting, particularly in the context of fever recovery and gastrointestinal illness. Multiple ethnobotanical reviews include nausea among the traditional indications of Aegle marmelos.

  • kudzuTraditional

    TCM and herbal traditions describe kudzu as useful for nausea, with herbalists particularly recommending it in combination with ginger tea. The traditional context relates to gastric heat and alcohol-related nausea. No controlled clinical trials for nausea and vomiting have been published.

  • lemon balmTraditional

    Lemon balm has a long and well-documented traditional history as a remedy for nausea, vomiting, and upset stomach in European and Iranian herbalism, with recognition in the German Commission E and the Iranian Herbal Pharmacopoeia. Clinical trial evidence specifically for nausea/vomiting as an isolated endpoint is lacking; the evidence base is primarily traditional/pharmacopoeial.

  • lemongrassTraditional

    Lemongrass is documented in folk medicine as an antiemetic (anti-nausea) and digestive remedy. Traditional use for nausea, indigestion, and gastrointestinal complaints is widely noted in pharmacological reviews of C. citratus. No human clinical trials specifically assessing lemongrass for nausea or vomiting have been identified.

  • licorice rootTraditional

    Licorice root has a long traditional use as a digestive carminative and for gastric upset in Chinese, Ayurvedic, and Middle Eastern medicine. Its demulcent and anti-spasmodic properties are proposed to relieve nausea. Direct clinical evidence specifically for nausea and vomiting as primary endpoints is lacking; most gastric evidence relates to ulcers and GERD rather than nausea specifically.

  • lilacTraditional

    The use of Syringa species to treat vomiting is documented in traditional Chinese medicine and cited in peer-reviewed genus reviews. This represents a consistently recorded traditional gastrointestinal indication across the literature.

  • lobeliaTraditional

    Lobelia's most historically prominent property is its powerful emetic action, deliberately used by both Native Americans and 19th-century Eclectic physicians. It was intentionally employed to induce vomiting for therapeutic "cleansing" or poisoning antidotes. At sub-emetic doses, its effects on nausea are bidirectional.

  • malabar nutTraditional

    Adhatoda vasica is listed in Ayurvedic texts as useful for nausea and vomiting. Traditional Ayurvedic documentation includes these symptoms among the conditions treated by A. vasica preparations.

  • marjoramTraditional

    In traditional herbal medicine, marjoram is classified as a stomachic—an herb that settles the stomach—and is used for nausea. Its carminative and digestive-stimulant properties underpin this use.

  • mugwortTraditional

    Mugwort has been historically classified as a digestive and antiemetic herb in traditional European and Asian medicine. Its antispasmodic action on smooth muscle and its documented use against nausea — including fever-related nausea — are found in multiple ethnobotanical records. No human clinical trials exist for this indication.

  • myrobalanTraditional

    TC is listed in folk and Ayurvedic medicine for vomiting and hiccough. Iranian traditional medicine and multiple South Asian folkloric sources cite TC as useful for nausea and upper gastrointestinal distress, attributed to its stomachic and prokinetic properties.

  • orangeTraditional

    Orange peel and its essential oil have documented traditional use for nausea and vomiting across multiple medical traditions, including Chinese traditional medicine. The aromatic compounds in orange peel—particularly d-limonene—are traditionally used as antiemetic agents. Clinical evidence specific to Citrus sinensis for nausea is limited.

  • partheniumTraditional

    Nausea and vomiting—particularly migraine-associated nausea—are cited as traditional indications for feverfew across multiple authoritative sources including the PMC systematic review. Feverfew is 'primarily known for use in prophylaxis of migraine headaches and associated nausea and vomiting' per Drugs.com. No dedicated clinical trials for nausea or vomiting as independent endpoints exist.

  • paw pawTraditional

    In homeopathic and traditional medicine contexts, paw paw (both Asimina triloba and Carica papaya) has been used for nausea and vomiting. Carica papaya is documented in traditional Asian and African medicine for gastrointestinal upset including nausea. No dedicated controlled clinical trials confirm anti-emetic efficacy.

  • peachTraditional

    Peach leaves have a long history of use across multiple traditional systems—TCM, Eclectic medicine, Ayurveda, and Appalachian folk herbalism—for reducing nausea and vomiting. The leaf is classified as antiemetic and demulcent. No human clinical trials have been conducted.

  • perillaTraditional

    Perilla is well-established in TCM for relieving nausea and vomiting, including pregnancy-related nausea. Its role in regulating qi and addressing digestive reversal (ascending stomach qi) is documented in classical texts including the Compendium of Materia Medica. No controlled human clinical trials for nausea and vomiting have been identified.

  • pineappleTraditional

    Fresh pineapple has been used in traditional medicine for nausea and digestive upset. The enzymes aid digestion of proteins that can cause gastric irritation, and the fruit is included in traditional preparations for morning sickness and general nausea in several indigenous traditions.

  • pistacia integerrima gallTraditional

    Pistacia integerrima galls are documented in Ayurvedic and folk medicine specifically for vomiting in children and dyspeptic vomiting. Multiple ethnopharmacological reviews and pharmacognostic surveys consistently record this antiemetic traditional use. Extracts from the galls are described as having antiemetic and carminative properties.

  • poppyTraditional

    Traditional use of poppy for nausea is documented in Unani and historical European medicine, where poppy preparations were used to suppress nausea and gastrointestinal upset. However, the opioid alkaloids themselves can paradoxically cause nausea at certain doses, and this relationship is complex.

  • schisandrinsTraditional

    Classical TCM monographs document Wu Wei Zi (Schisandra) for stomach disorders and GI complaints. MSKCC notes its historical use for 'stomach disorders.' No human RCTs specifically testing schisandrins for nausea or vomiting have been identified.

  • shen-chuTraditional

    Classical TCM texts indicate shen-chu for nausea and vomiting associated with food stagnation and summer-heat syndrome. It appears in multi-herb TCM formulas investigated for chemotherapy-induced nausea and vomiting, but direct clinical evidence for shen-chu alone is absent.

  • sichuan pepperTraditional

    TCM classical texts list vomiting and stomach cold as primary indications for Hua Jiao (Z. bungeanum). Its warming, pro-motility effects on the gastrointestinal tract provide a mechanistic rationale, though no human clinical trial evidence is available.

  • slippery elmTraditional

    Slippery elm is traditionally used for gastrointestinal upset including nausea. A small multi-ingredient clinical study found improvement in nausea, though slippery elm's individual contribution cannot be isolated. Traditional use for general GI disturbance including nausea is well documented.

  • slippery elm barkTraditional

    Slippery elm has been traditionally used for nausea and stomach upset. An Australian multi-ingredient clinical study including slippery elm reported reduced nausea among participants with digestive disorders. However, slippery elm has not been studied in isolation for nausea, and attribution cannot be confirmed.

  • star of bethlehemTraditional

    In homeopathic Materia Medica (Boericke), Ornithogalum umbellatum has a well-described traditional indication for nausea, vomiting, and 'phlegmy retchings' associated with severe gastric pathology, including gastric ulceration and pyloric dysfunction. Vomiting of coffee-ground material is listed as a keynote symptom. This is a traditional homeopathic indication without clinical trial evidence.

  • sweet flagTraditional

    A. calamus has traditional use across Ayurveda, Unani, and Native American medicine for nausea and vomiting, particularly in the context of digestive disorders. It is listed in Unani texts as a stomach tonic and gastrointestinal remedy. No clinical trial data specific to nausea/vomiting exist.

  • swertiaTraditional

    Swertia chirayita has been traditionally used for vomiting and nausea in Ayurvedic and folk medicine throughout South Asia. The comprehensive J Ethnopharmacol 2023 review lists vomiting among its traditional indications. No human clinical data specifically addressing nausea or vomiting endpoints are available.

  • tinospora cordifoliaTraditional

    T. cordifolia is documented in traditional Indian medicine texts as a remedy for vomiting and digestive complaints. Its antispasmodic and digestive properties provide mechanistic rationale. ScienceDirect review lists it as used for fever, vomiting, diabetes, and jaundice in traditional practice.

  • vanillaTraditional

    Vanilla has a documented traditional use for nausea and gastrointestinal irritation. Multiple historical pharmacopoeias and materia medica texts describe its use as a carminative and gastrointestinal soother. No clinical human trials have investigated vanilla specifically for nausea or vomiting.

  • wild yamTraditional

    Wild yam has a long traditional history as an antispasmodic remedy for nausea, vomiting, and gastrointestinal cramping. 19th-century Eclectic physicians frequently prescribed it for bilious colic and persistent nausea. No controlled clinical trials substantiate this use in humans.

  • wood betonyTraditional

    Wood betony is listed in traditional herbal records as a stomachic remedy for nausea, particularly that associated with weak or stressed digestion. Historical herbalists Menzies-Trull and others note its tonic action on the stomach for nausea. No clinical data exist.

  • zanthoxylumTraditional

    Zanthoxylum is listed in the Chinese Pharmacopoeia and multiple TCM traditions for use in vomiting and nausea. Traditional preparations are used across Asia for these complaints. Antispasmodic properties provide indirect mechanistic plausibility, but no clinical studies exist.

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Nausea and Vomiting | Vitabase