Ammonium glycyrrhizinate
Synopsis of Ammonium glycyrrhizinate
History
Ammonium glycyrrhizinate is a salt derived from glycyrrhizic acid, the primary active constituent of licorice root (Glycyrrhiza glabra). Licorice root has been treasured for thousands of years, with historical records of its use dating back to ancient Egypt, China, and Greece. In traditional Chinese medicine, licorice—known as "Gan Cao"—has been included in countless herbal formulas to harmonize and enhance the effects of other herbs. In ancient Greece, Hippocrates praised it for its soothing properties, especially in treating coughs and respiratory complaints.
Ammonium glycyrrhizinate, as a refined extract, has been recognized for its sweet flavor and potent medicinal benefits. Traditionally, it has been used as a remedy for sore throats, coughs, and digestive issues, owing to its anti-inflammatory, demulcent, and expectorant properties. Its ability to modulate the immune response has been valued in supporting recovery from colds and minor infections. Moreover, it has been used to ease stomach discomfort and promote gastrointestinal health.
In herbal combinations, ammonium glycyrrhizinate continues the legacy of licorice as a harmonizing agent. It not only enhances the efficacy of other botanical ingredients but also helps mitigate potential side effects, making multi-herb formulas more balanced and effective. Its presence in modern nutritional products demonstrates its enduring value and adaptability. The positive impact of ammonium glycyrrhizinate is supported by both tradition and contemporary research, highlighting its important role in promoting wellness, supporting respiratory health, and maintaining digestive comfort.
Traditional and scientific validation
Ammonium glycyrrhizinate is a salt form of glycyrrhizic acid, the principal sweet-tasting component derived from licorice root (Glycyrrhiza glabra). Historically, licorice has been used for thousands of years in traditional medicine systems, such as Traditional Chinese Medicine and Ayurveda, to support digestive health, soothe sore throats, and promote general wellness. The isolation and use of ammonium glycyrrhizinate in nutritional products reflects an effort to harness the beneficial properties of licorice in a more standardized and bioavailable form.
Scientific studies have identified ammonium glycyrrhizinate as possessing notable anti-inflammatory, antioxidant, and hepatoprotective (liver-protecting) effects. Experimental research suggests that it can modulate immune responses and inhibit inflammatory mediators, which may contribute to its potential in supporting immune and liver health. Some clinical trials and animal studies have reported beneficial outcomes, such as reduced markers of liver damage and improved symptoms in certain inflammatory conditions. In the food and nutraceutical industries, ammonium glycyrrhizinate is also valued for its sweetening properties and its role as a flavor enhancer, offering a natural alternative to synthetic additives.
While these findings are promising, it is important to note that more large-scale, well-designed human studies are required to firmly establish the efficacy and safety of ammonium glycyrrhizinate when used as a supplement. Current evidence supports its traditional uses and indicates a favorable safety profile at recommended dosages, making it a valuable ingredient in nutritional products. Continued research will further clarify its potential contributions to human health.
Ammonium glycyrrhizinate is used for these health conditions
Acid Indigestion (Traditional)
Antibiotics (side effects of) (Traditional)
Asthma (Traditional)
Bronchitis (Traditional)
Cirrhosis of the Liver (Traditional)
Cold Sores (Traditional)
Colds (antiviral) (Traditional)
Colds (decongestant) (Traditional)
Colds (general) (Traditional)
Colds (prevention) (Traditional)
Colitis (Traditional)
Congestion (bronchial) (Traditional)
Congestion (lungs) (Traditional)
Convalescence (Traditional)
Cough (general) (Traditional)
Cough (spastic) (Traditional)
Diarrhea (Traditional)
Duodenal Ulcers (Traditional)
Gastritis (Traditional)
Hepatitis (Traditional)
Indigestion (Traditional)
Infection (Traditional)
Infection (bacterial) (Traditional)
Infection (viral) (Traditional)
Inflammation (Traditional)
Inflammatory Bowel Disorders (Traditional)
Liver Detoxification (Traditional)
Oral Surgery (Traditional)
Pain (general remedies for) (Traditional)
Psoriasis (Traditional)
Skin (infections) (Traditional)
Sore Throat (Traditional)
Staph Infections (Traditional)
Ulcers (Traditional)
Wounds and Sores (Traditional)
Ammonium glycyrrhizinate is used to support these body systems
Adrenal Glands (Traditional)
Gastrointestinal Tract (Scientific)
Liver (Traditional)
Respiratory System (Scientific)
Skin (Scientific)