Caffeoylquinic acids
Other names for caffeoylquinic acids
3, 4 & 5 caffeoylquinic acids
3-4-5 caffeoylquinic acids
5-caffeolyquinic acid
5-caffeoylquinic acid
caffeolyquinic acid derivatives
caffeoyl acid
caffeoylquinic acid
caffeoylquinic acid derivatives
caffeoylquinic acids
caffeylquinic acids
cynarin
cynarine
cynarins
dicaffeoylquinic acid
dicaffeoylquinic acids
Synopsis of caffeoylquinic acids
History
Caffeoylquinic acids, a group of naturally occurring polyphenolic compounds, have a rich history of medicinal use, especially within traditional herbal remedies. These compounds, most notably chlorogenic acid, are abundant in a variety of plants such as coffee beans, artichoke, echinacea, and burdock root. Historically, caffeoylquinic acids have been valued in folk medicine for their broad spectrum of health-promoting properties.
Ancient herbalists often utilized plants rich in caffeoylquinic acids to prepare tonics and decoctions aimed at supporting liver health, promoting detoxification, and enhancing digestive function. In traditional European and Asian medicine, artichoke leaf extracts—high in these acids—were prescribed to stimulate bile flow and alleviate symptoms of indigestion. Similarly, Native American healers incorporated echinacea and burdock into their remedies, recognizing their potential to support immune function and promote overall wellness.
Herbal combinations featuring caffeoylquinic acid-rich plants remain popular due to their synergistic effects. For example, blends of green coffee bean, dandelion root, and artichoke are commonly utilized for metabolic and antioxidant support. These combinations harness the potent antioxidant, anti-inflammatory, and hepatoprotective properties of caffeoylquinic acids, contributing to improved energy, immune resilience, and detoxification. Their inclusion in modern nutritional products reflects a continued appreciation for their historical uses, offering a bridge between traditional wisdom and contemporary health practices. Overall, caffeoylquinic acids have made significant positive contributions to herbal medicine, supporting vitality and well-being through centuries of use.
Traditional and scientific validation
Caffeoylquinic acids, a group of polyphenolic compounds primarily found in coffee, artichokes, and various fruits and vegetables, have garnered increasing attention as functional ingredients in nutritional products. Historically, plants rich in caffeoylquinic acids have been used in traditional medicine for their perceived health benefits, including liver protection and anti-inflammatory effects. The most common form, chlorogenic acid, is especially abundant in green coffee beans and has been associated with a range of physiological activities.
Scientific research has provided preliminary evidence supporting some of these traditional uses. In vitro and animal studies suggest that caffeoylquinic acids possess antioxidant, anti-inflammatory, and hepatoprotective properties. Small-scale human clinical trials have explored their potential in modulating blood glucose levels, supporting weight management, and reducing cardiovascular risk factors. For example, some studies indicate that chlorogenic acid may aid in the regulation of blood sugar and lipid metabolism, contributing to the popularity of green coffee extract in nutritional supplements.
Despite these promising findings, the clinical evidence remains limited and sometimes inconsistent. Larger and long-term studies are needed to confirm the efficacy and safety of caffeoylquinic acids in humans. Nonetheless, due to their antioxidant potential and the positive preliminary results, caffeoylquinic acids continue to be valued as functional components in nutritional formulations. Ongoing research is expected to further elucidate their mechanisms of action and potential health benefits.
Caffeoylquinic acids is used for these health conditions
Cancer (natural therapy for) (Scientific)
Cancer (prevention) (Scientific)
Cardiovascular Disease (Scientific)
Colitis (Scientific)
Diabetes (Scientific)
Digestion (poor) (Traditional)
Free Radical Damage (Scientific)
Gastritis (Scientific)
Hypertension (Scientific)
Inflammation (Scientific)
Liver Detoxification (Scientific)
Triglycerides (high) (Scientific)
caffeoylquinic acids is used to support these body systems
Digestive System (Traditional)
Heart (Scientific)
Immune System (Scientific)
Intestinal System (Scientific)
Liver (Scientific)