Eleutheroside
Other names
0.8% eleutherosides
b&e eleutherosides
eleutheroside
eleutheroside b
eleutheroside e
eleutherosides
eleutherosides b & e
eleutherosides b+e
eleutherosides e and b
eleutherosides e&b
eleutherosides extract
eleutherosides std. ext
eleutherosides std. ext.
eleuthrosides
standardized to provide 1.6 mg eleutherosides
total eleutherosides
Synopsis
History
Eleutheroside refers to a group of active compounds found in Eleutherococcus senticosus, commonly known as Siberian ginseng. For centuries, this plant has held a revered place in traditional medicine, particularly within Russia, China, and neighboring regions. Historically, Siberian ginseng was prized for its adaptogenic properties—helping the body resist physical, mental, and environmental stress. Herbalists and healers used preparations containing eleutherosides to boost vitality, enhance endurance, and support immune function. It was a cornerstone remedy for promoting overall well-being, increasing stamina, and aiding recovery after illness or fatigue.
In folk remedies, decoctions and tinctures of Siberian ginseng were commonly administered to improve mental clarity, reduce feelings of tiredness, and restore balance during times of stress. Eleutherosides, as the bioactive components, are believed to be responsible for these benefits, working synergistically to support energy metabolism and bolster resilience.
Modern herbal practice often utilizes eleutheroside-rich extracts in combination with other adaptogenic herbs such as rhodiola, schisandra, and ashwagandha. These blends are formulated to optimize the adaptogenic effects, collectively enhancing the body’s capacity to cope with stress, maintain energy, and protect against immune challenges. The inclusion of eleutherosides in such herbal combinations has contributed greatly to their popularity, especially among those seeking natural ways to support health and performance.
Overall, eleutherosides have made a significant contribution to both traditional and contemporary herbal medicine, providing a natural, effective means to promote wellness, resilience, and vitality.
Traditional and scientific validation
Eleutheroside is a group of active compounds found in Eleutherococcus senticosus, commonly known as Siberian ginseng. Traditionally, this plant has been used in Russian and Chinese herbal medicine for centuries, primarily as an adaptogen—a substance believed to help the body resist physical, chemical, and biological stress. Eleutherosides, particularly eleutheroside B and E, are considered the principal bioactive constituents responsible for the plant’s therapeutic effects.
Over the past few decades, both preclinical and clinical studies have investigated the potential benefits of eleutherosides. Some research suggests that eleutherosides may help enhance physical performance, reduce fatigue, and support immune function. For instance, several clinical trials conducted in the former Soviet Union reported improved stamina and mental alertness among athletes and workers taking Siberian ginseng extracts. Additionally, laboratory studies indicate that eleutherosides may modulate stress responses by influencing the hypothalamic-pituitary-adrenal (HPA) axis, and may also exhibit antioxidant and anti-inflammatory properties.
However, while these findings are promising, comprehensive clinical validation of eleutherosides’ efficacy and safety is still evolving. Many studies to date have been limited by small sample sizes, varying extract formulations, and inconsistent methodologies. As a result, more rigorous, large-scale clinical trials are needed to confirm and better understand the health benefits attributed to eleutherosides.
Despite these limitations, eleutheroside-containing supplements continue to be valued in nutritional products for their traditional use and emerging scientific support. They represent a promising natural option for those seeking to enhance general well-being and resilience to stress.
Uses: Health Conditions
Adrenal Fatigue (Traditional)
Anxiety (Traditional)
Athletic and Exercise Aids (Traditional)
Cancer (natural therapy for) (Traditional)
Cancer Treatment (reducing side effects) (Traditional)
Cardiovascular Disease (Traditional)
Circulation (poor) (Traditional)
Depression (Traditional)
Diabetes (Traditional)
Energy (lack of) (Traditional)
Fatigue (Scientific)
Free Radical Damage (Scientific)
Inflammation (Scientific)
Memory and Brain Function (Traditional)
Muscle Tone (lack of) (Traditional)
Nervous Exhaustion (Traditional)
Nervousness (Traditional)
Stress (Traditional)
Wounds and Sores (Traditional)
Body Systems
Adrenal Cortex (Traditional)
Adrenal Glands (Traditional)
Adrenal Medulla (Traditional)
Brain (Traditional)
Circulatory System (Traditional)
Cortisol (Traditional)
Glandular System (Traditional)
Hypothalamus (Traditional)
Immune System (Traditional)
Lymphatics (Traditional)
Nerves (Traditional)
Pituitary (Traditional)
Respiratory System (Traditional)
Spleen (Traditional)