Glycine propionyl-l-carnitine
Other names for Glycine propionyl-l-carnitine
glycine propiony l-carnitine hydrochloride
glycine propionyl l-carnitine
glycine propionyl-l-carnitine
glycine propionyl l carnitine hcl
glycine propionyl l-carnitine hcl
glycine propionyl-l-carnitine hcl
glycine-propionyl-l-carnitine hcl
glycine propionyl l-carnitine hydrochloride
glycine proprionyl l-carnitine hcl
glycocarn
glycocarn glycine propionyl l-carnitine hcl
glycocarn glycine propionyl-l-carnitine hcl
glycocarn glycine propionyl-l-carnitine hydrochloride
glycocarn gplc
glycocarn-gplc
glycocarn (gplc) glycine propionyl-l-carnitine hcl
glycocarn(r)
glycocarn(r) gplc
glycocarn(r) gplc complex
glycocarn(tm)
gplc
Synopsis of Glycine propionyl-l-carnitine
History
Glycine propionyl-L-carnitine (GPLC) is a unique nutritional compound composed of glycine, an amino acid, and propionyl-L-carnitine, a specialized form of the nutrient L-carnitine. While GPLC itself is a relatively recent innovation in the realm of dietary supplements and sports nutrition, its components have rich historical roots in medicinal and therapeutic use.
L-carnitine, discovered in the early 20th century, gained attention for its crucial role in cellular energy production and fat metabolism. Traditionally, carnitine and its derivatives have been used to support cardiovascular health, enhance physical performance, and improve recovery from fatigue. Glycine, on the other hand, has been utilized since ancient times for its calming and restorative properties, often featured in tonics and remedies for sleep, digestion, and muscle health.
The combination of glycine and propionyl-L-carnitine in GPLC creates a synergistic supplement that supports circulation, energy, and antioxidant defense. Research has shown that GPLC can promote nitric oxide production, thereby improving blood flow and exercise performance. This makes it a valuable tool for athletes and individuals seeking to optimize cardiovascular and muscular health.
In the context of herbal combinations, GPLC is frequently paired with antioxidant-rich botanicals such as green tea extract, ginkgo biloba, and grape seed extract. These blends are designed to amplify circulatory and metabolic benefits, supporting overall vitality and resilience. The unique properties of GPLC make it a standout component in contemporary wellness formulas, reflecting the enduring value of amino acid-based remedies in both traditional and modern health practices.
Traditional and scientific validation
Glycine propionyl-L-carnitine (GPLC) is a compound formed by combining propionyl-L-carnitine, an amino acid derivative involved in energy production, with glycine, an amino acid with various physiological roles. GPLC has been utilized as a dietary supplement, particularly in the context of sports nutrition and cardiovascular health.
Historically, the use of carnitine derivatives like propionyl-L-carnitine dates back several decades, with initial research focusing on their potential to support mitochondrial energy metabolism and cardiovascular function. The unique addition of glycine in GPLC is thought to enhance its bioavailability and functional properties.
Several clinical studies have explored the effects of GPLC supplementation. Research suggests that GPLC may improve blood flow and nitric oxide production, which are important factors for exercise performance and cardiovascular health. For example, some studies have reported that GPLC supplementation in athletes may increase plasma nitrate/nitrite levels, potentially supporting enhanced exercise performance, reduced fatigue, and improved recovery. Additionally, there is interest in its antioxidant properties and its possible role in reducing oxidative stress during intense physical activity.
Despite these promising findings, the body of scientific evidence remains limited, and more large-scale, long-term clinical trials are needed to fully validate the effects and safety of GPLC supplementation. While effects have not been definitively proven, GPLC continues to be a focus of research and is regarded as a promising ingredient for supporting energy metabolism and vascular health in both athletes and the general population.
Glycine propionyl-l-carnitine is used for these health conditions
Angina (Scientific)
Cardiovascular Disease (Scientific)
Circulation (poor) (Scientific)
Congestive Heart Failure (Scientific)
Exercise (Scientific)
Fatigue (Scientific)
Peripheral Neuropathy (Scientific)
Raynaud's Disease (Scientific)
Glycine propionyl-l-carnitine is used to support these body systems
Arteries (Scientific)
Blood (Scientific)
Circulatory System (Scientific)
Heart (Scientific)
Mitochondria (Scientific)
Muscles (Scientific)