Guarana (paullinia cupana)

Links: Go back one page, Tool main page, Ingredients list, Health conditions list, Body systems list

Other names for guarana

guarana

Synopsis of guarana

Guarana (Paullinia cupana) is a climbing shrub native to the Amazon rainforest, particularly in Brazil, and is most famous for its small red fruit that contains seeds rich in natural caffeine. These seeds are among the most concentrated natural sources of caffeine—containing 2 to 4 times more caffeine than coffee beans. Guarana also contains theobromine, theophylline, saponins, tannins, and catechins, contributing to its stimulant, antioxidant, cognitive-enhancing, and thermogenic effects.

In modern use, guarana is a popular ingredient in energy drinks, pre-workout supplements, weight management formulas, and cognitive enhancers. It helps increase alertness, mental focus, and physical endurance, and may also enhance fat oxidation and metabolic rate, making it useful for those seeking appetite control and energy without synthetic stimulants. Its tannin content allows for slower absorption of caffeine, providing a smoother and longer-lasting energy boost than coffee.

Beyond stimulation, guarana’s antioxidant properties may support cardiovascular health and cellular defense, and its astringent compounds can contribute to digestive support and antimicrobial effects.

Historical Use
Guarana has been used for centuries by the Indigenous peoples of the Amazon, such as the Guaraní and Sateré-Mawé tribes, who regarded it as a sacred plant and daily tonic. They prepared it by drying, roasting, and grinding the seeds into a paste, then shaping it into cylinders that were grated into water to create a stimulating beverage used to reduce fatigue, hunger, and heat stress, particularly during long hunts or periods of exertion.

The name “guarana” itself comes from the Guaraní word warana, meaning “fruit like the eyes of the people,” referring to the seed’s appearance when the fruit is split open. The plant was also used in traditional medicine to treat headaches, fever, cramps, diarrhea, and as an aphrodisiac or remedy for heat-related illnesses.

European colonists adopted guarana in the 17th and 18th centuries, using it as a natural stimulant and incorporating it into early pharmaceutical preparations. By the 20th century, it was commercialized in soft drinks and herbal supplements, particularly in Brazil, where it remains a national symbol of vitality.

Today, guarana is recognized globally as a natural performance enhancer and mental stimulant, continuing its legacy as one of nature’s most potent sources of plant-based energy and endurance support.

Guarana is used for these health conditions

Athletic and Exercise Aids (Scientific)
Concentration (poor) (Scientific)
Energy (lack of) (Scientific)
Fatigue (Scientific)
Free Radical Damage (Scientific)
Memory and Brain Function (Scientific)
Weight Loss (Scientific)

guarana is used to support these body systems

Brain (Scientific)
Nerves (Traditional)
Sympathetic Nervous System (Scientific)

Products containing guarana

Designs For Health Thermo-EFx™

Additional Help

Talk with Dr. Shannyn

Get to the root of what’s really going on.
Symptoms like fatigue, bloating, skin issues, or mood changes often point to deeper imbalances. Our at-home lab tests make it easy to investigate hormone health, gut function, food sensitivities, and more—no clinic visit required.

Schedule a Free Consult →
Personalized support. No pressure. No cost.

At-Home Lab Testing

Want to know if your body really needs this ingredient?
Explore our at-home lab tests—from hormone and gut panels to toxin screenings. These simple kits give you data to back your decisions, and pair perfectly with natural ingredient guidance.

Explore Lab Testing →
Results interpreted with expert support. No clinic visit required.