Other names for Polydimethylsiloxane

dimethicone
dimethylpolysiloxane
dimethyl siloxane
polydimethylsiloxane

Synopsis of Polydimethylsiloxane

History

Polydimethylsiloxane (PDMS), also known as dimethicone, has a long-standing history of use in medicinal and nutritional products, particularly valued for its safety and versatility. Since its introduction in the mid-20th century, PDMS has been widely incorporated into remedies targeting digestive issues. Its primary medicinal application has been as an anti-foaming agent, effectively reducing bloating and discomfort caused by excess gas in the gastrointestinal tract. Over-the-counter remedies for flatulence and colic, especially in infants and children, often feature PDMS for its ability to break up gas bubbles, providing gentle and rapid relief.

Beyond its standalone benefits, PDMS has played a significant role in enhancing herbal combinations and nutritional supplements. Its unique chemical inertness means it does not react with active botanical ingredients, ensuring the stability and effectiveness of complex formulations. In herbal medicine, PDMS is sometimes combined with traditional digestive herbs like fennel, peppermint, or ginger, amplifying their soothing effects on the digestive system. By facilitating the dispersion of herbal extracts and aiding in the even distribution of active compounds, PDMS helps optimize the bioavailability of these natural remedies.

Overall, polydimethylsiloxane has made invaluable contributions to modern medicine and nutrition. Its proven safety profile, coupled with its compatibility with both synthetic and herbal ingredients, makes it a cornerstone in the development of gentle, effective remedies that support digestive health and general wellness.

Traditional and scientific validation

Polydimethylsiloxane (PDMS) is a silicon-based organic polymer widely used in the food and pharmaceutical industries, primarily as an anti-foaming agent. Its inclusion in nutritional products dates back to the mid-20th century, following regulatory approval for use in food processing and manufacturing. The U.S. Food and Drug Administration (FDA) has classified PDMS as Generally Recognized As Safe (GRAS) for specific applications, such as preventing excessive foaming during the production of beverages and certain processed foods.

Scientifically, PDMS is valued for its chemical inertness and stability, which minimize the risk of adverse reactions within the human body. Several studies have investigated its safety profile, revealing minimal absorption through the gastrointestinal tract and rapid excretion. For example, animal studies and limited human data suggest that PDMS passes through the digestive system unchanged, thus supporting its safety as a food additive. Moreover, its use in pharmaceutical formulations, such as simethicone, underscores its effectiveness in alleviating symptoms of bloating and gastrointestinal discomfort by reducing surface tension and dispersing gas bubbles.

While the historical and scientific record supports PDMS’s safety for specific purposes, comprehensive clinical studies on its long-term effects in humans remain limited. Continued research is warranted to fully elucidate its potential health impacts and therapeutic benefits. Nonetheless, the historical track record and regulatory approvals indicate that PDMS is a valuable and trusted ingredient in modern nutritional products, contributing to improved product quality and consumer experience.

Polydimethylsiloxane is used for these health conditions

Acid Indigestion (Scientific)
Gas and Bloating (Scientific)
Indigestion (Scientific)

This ingredient is used to support these body systems

None

Products containing Polydimethylsiloxane

We currently have no products on Vitabase that contain this ingredient.