Pyrroloquinoline quinone disodium salt
Synopsis of Pyrroloquinoline quinone disodium salt
History
Pyrroloquinoline quinone disodium salt (PQQ) is a powerful antioxidant compound that has gained attention in recent decades for its remarkable benefits in nutritional and medicinal products. Although PQQ itself was only identified in the late 20th century, its presence is intrinsic to many traditional remedies, as it naturally occurs in a variety of foods such as fermented soybeans, green tea, and certain medicinal herbs. Historically, these PQQ-rich foods and herbs have been staples in folk medicine, revered for their rejuvenating and restorative properties.
In the context of traditional remedies, substances now known to be high in PQQ were often used to support vitality, enhance cognitive function, and promote longevity. For instance, fermented foods, a natural source of PQQ, have been employed in diverse cultures to bolster immune health and digestive wellness. The underlying science, only recently elucidated, demonstrates that PQQ supports mitochondrial biogenesis and protects cells from oxidative stress, which aligns with the observed benefits in ancient herbal practices.
PQQ's incorporation into modern herbal combinations is especially promising. When blended with botanicals such as ginkgo biloba, ashwagandha, or curcumin, PQQ may amplify their neuroprotective and anti-inflammatory effects, creating synergistic formulas that promote mental clarity, energy, and overall well-being. Its compatibility with both traditional and contemporary herbal preparations underscores its versatile role in health maintenance. Overall, PQQ disodium salt stands as a testament to the enduring power of nature’s remedies, now validated by modern science for its profound contributions to human health.
Traditional and scientific validation
Pyrroloquinoline quinone disodium salt (PQQ) is a redox cofactor discovered in the late 1970s, initially recognized for its role in bacterial enzymatic processes. Subsequent research identified PQQ as a compound present in various foods, including kiwifruit, green peppers, and fermented soybeans. Its inclusion in nutritional products has been driven by preclinical studies suggesting roles in cellular energy metabolism, antioxidant defense, and mitochondrial biogenesis.
Animal studies have demonstrated that PQQ supplementation may support mitochondrial function and protect cells from oxidative stress. In particular, research in rodents has shown improved learning ability, memory, and neuroprotection, leading to interest in its potential cognitive benefits for humans.
Clinical trials in humans remain limited but promising. A notable double-blind, placebo-controlled study published in 2009 found that healthy adults taking PQQ experienced improvements in subjective fatigue and sleep quality. Another small-scale study reported enhanced attention and cognitive performance when PQQ was combined with coenzyme Q10. These early findings suggest PQQ may contribute to overall mental and physical well-being, although larger and longer-term studies are needed to confirm these effects and establish optimal dosages.
Overall, while scientific validation for PQQ’s health benefits is still evolving, existing evidence highlights its function as a potent antioxidant and mitochondrial modulator. Its safety profile in nutritional applications appears favorable, and ongoing research may further elucidate its role in supporting human health.
Pyrroloquinoline quinone disodium salt is used for these health conditions
Aging (prevention) (Scientific)
Alzheimer's Disease (Scientific)
Athletic and Exercise Aids (Scientific)
Cardiovascular Disease (Scientific)
Depression (Scientific)
Diabetes (Scientific)
Energy (lack of) (Scientific)
Fatigue (Scientific)
Free Radical Damage (Scientific)
Inflammation (Scientific)
Memory and Brain Function (Scientific)
Stress (Scientific)
Pyrroloquinoline quinone disodium salt is used to support these body systems
Brain (Scientific)
Circulatory System (Scientific)
Heart (Scientific)
Mitochondria (Scientific)
Nerves (Scientific)