Scopoletin

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Other names for Scopoletin

30 ppm scopoletin
scopoletin

Synopsis of Scopoletin

History

Scopoletin is a naturally occurring coumarin compound found in a variety of plants, such as Morinda citrifolia (noni), Scopolia carniolica, and certain Artemisia and Magnolia species. Historically, scopoletin-rich plants have been prized in traditional medicine systems across various cultures. For centuries, healers used extracts containing scopoletin to address ailments such as inflammation, fever, respiratory issues, and infections. Folk remedies often employed these botanicals as tonics for promoting overall vitality, relieving pain, and supporting digestive health.

In ethnomedicine, scopoletin-bearing herbs were commonly utilized in the treatment of wounds, arthritis, and even as mild sedatives due to their calming effects. In the tropics, noni fruit juice—rich in scopoletin—has been consumed for generations to support immune function and cardiovascular health. Scopoletin’s reputed ability to balance serotonin levels contributed to its use in mood-enhancing herbal preparations, demonstrating its versatility.

Herbalists often combine scopoletin-rich ingredients with other botanicals to amplify their therapeutic effects. For example, blends with turmeric, ginger, or licorice are believed to synergistically boost anti-inflammatory and antioxidant benefits. In modern times, scopoletin continues to attract attention for its positive contributions, including its potential to support healthy blood pressure, modulate immune response, and protect cells from oxidative damage. Its enduring role in traditional and contemporary remedies underscores the valuable place of scopoletin in natural health practices, both as a standalone constituent and as part of holistic herbal combinations.

Traditional and scientific validation

Scopoletin is a naturally occurring coumarin compound found in various plants, including noni fruit (Morinda citrifolia), passionflower, and some herbs historically used in traditional medicine. Its inclusion in nutritional products is largely based on its long-standing reputation for health-promoting properties in folk remedies. Historically, scopoletin-rich plants were utilized in traditional systems across Polynesia, Asia, and South America for their purported anti-inflammatory, antipyretic, and analgesic effects.

Scientific interest in scopoletin has grown over the past few decades. Laboratory and animal studies suggest that scopoletin possesses antioxidant, anti-inflammatory, and neuroprotective activities. For example, research has indicated that scopoletin may help reduce oxidative stress by scavenging free radicals and modulating enzymes involved in inflammation. Some studies have also explored its potential to support healthy blood pressure levels and improve metabolic profiles, though these effects have primarily been observed in preclinical models.

While promising, clinical evidence in humans remains limited. Few small-scale trials have investigated scopoletin-containing extracts, such as noni juice, reporting potential benefits for cardiovascular health and immune modulation. However, it is difficult to attribute these effects directly to scopoletin due to the presence of multiple bioactive compounds in these extracts. Therefore, while early results are encouraging, more rigorous, well-controlled human studies are necessary to confirm scopoletin’s specific health benefits and mechanisms of action.

In summary, scopoletin’s historical use and initial scientific findings support its inclusion in nutritional products, but further research is needed to fully validate its health claims. Its potential contributions as an antioxidant and anti-inflammatory agent continue to make it a valuable subject for ongoing nutritional science.

Scopoletin is used for these health conditions

Arthritis (Traditional)
Cancer (natural therapy for) (Scientific)
Diabetes (Scientific)
Free Radical Damage (Scientific)
Gastritis (Traditional)
Hypertension (Scientific)
Inflammation (Scientific)
Liver Detoxification (Scientific)
Pain (general remedies for) (Traditional)
Ulcers (Scientific)

Scopoletin is used to support these body systems

Digestive System (Traditional)
Gastrointestinal Tract (Traditional)
Liver (Scientific)
Skin (Traditional)

Products containing Scopoletin

We currently have no products on Vitabase that contain this ingredient.

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