Silybin
Other names for Silybin
15% silybin
isosilybin
isosilybin a
isosilybin a and isosilybin b
isosilybin b
isosilybin blend
providing 22.5 mg silybin
providing silybin
silibin
silibinin
silibinins
siliphos
siliphos(r) silybin phytosome(r)
siliphos(tm)
silybin
silybin a and silybin b
silybin a & b
silybin beta milk thistle
silybin concentrate
silybines
silybin extract
silybin extract complex
silybin-phosphatidylcholine complex
silybin phospholipid complex
silybin phospholipids
silybin phytosome
silybin phytosome complex
silybin phytosome(tm)
silybin (silybum marianum) extract
silybin (silybum marianum) fruit
silybin standardized
silybin-sunflower lecithin
total silybins
Synopsis of Silybin
History
Silybin, also known as silibinin, is the principal active component of silymarin, a standardized extract derived from the seeds of the milk thistle plant (Silybum marianum). Its medicinal applications trace back over 2,000 years, with roots in ancient Greco-Roman herbalism. Historically, milk thistle was prized for its remarkable ability to support liver health and was featured in remedies to counteract poisoning, particularly from mushroom ingestion, as well as to address jaundice, hepatitis, and a variety of hepatic disorders.
Throughout the centuries, silybin has been celebrated for its antioxidant, anti-inflammatory, and hepatoprotective properties. Traditional healers valued milk thistle seeds and extracts for their capacity to promote bile flow, enhance digestion, and aid in recovery from excessive alcohol consumption or exposure to environmental toxins. Folk remedies often included milk thistle as a restorative tonic for convalescents and individuals facing chronic liver conditions.
In modern herbal medicine, silybin is frequently used in combination with other botanicals to maximize therapeutic benefits. Herbal formulas often blend silybin with artichoke, dandelion root, turmeric, or schisandra, creating synergistic effects that amplify liver detoxification, regeneration, and overall well-being. These multi-herb supplements are popular among individuals seeking natural support for metabolic health and resilience against oxidative stress.
The enduring legacy and positive reputation of silybin in traditional and contemporary medicine highlight its invaluable contributions to holistic health. Its time-tested benefits continue to inspire confidence in both practitioners and those seeking natural avenues to maintain vitality and liver health.
Traditional and scientific validation
Silybin, also known as silibinin, is a primary active component of silymarin, an extract derived from the seeds of the milk thistle plant (Silybum marianum). Historically, milk thistle has been used for over 2,000 years in traditional medicine, particularly in Europe and the Mediterranean region, for supporting liver health and treating ailments such as jaundice and hepatitis.
Modern scientific research has begun to validate some of these traditional uses. Silybin is recognized for its antioxidant, anti-inflammatory, and hepatoprotective properties. Clinical studies have suggested that silybin may help protect liver cells from toxins, support liver regeneration, and reduce markers of liver damage, especially in conditions like non-alcoholic fatty liver disease and hepatitis. Some trials have also explored its potential benefits in improving insulin resistance, reducing cholesterol, and providing support in certain metabolic disorders.
Despite promising preclinical and clinical findings, the overall body of evidence remains mixed. Some studies report significant improvements in liver function tests and symptom relief, while others find minimal or no effect. The variability in study results is often attributed to differences in product formulations, dosages, and patient populations. As a result, while silybin demonstrates potential as a supportive agent for liver health and metabolic wellness, more large-scale, well-designed clinical trials are needed to conclusively establish its efficacy and optimal use.
Nevertheless, silybin continues to be a valued ingredient in nutritional supplements, with a long tradition of use and a growing scientific foundation supporting its role in promoting liver and overall health.
Silybin is used for these health conditions
Alcoholism (Scientific)
Cancer (natural therapy for) (Scientific)
Cancer (prevention) (Scientific)
Cancer Treatment (reducing side effects) (Scientific)
Cirrhosis of the Liver (Scientific)
Fatty Liver Disease (Scientific)
Hepatitis (Scientific)
Inflammation (Scientific)
Liver Detoxification (Scientific)
Radiation Sickness (Scientific)
Triglycerides (high) (Scientific)
Silybin is used to support these body systems
Digestive System (Scientific)
Gastrointestinal Tract (Scientific)
Hepatic System (Scientific)
Liver (Scientific)