Sodium carboxymethyl cellulose

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Other names for sodium carboxymethyl cellulose

ac-di-sol

Synopsis of sodium carboxymethyl cellulose

History

Sodium carboxymethyl cellulose (CMC) is a cellulose derivative with a long and valuable history in medicinal and nutritional applications. First introduced in the early 20th century, CMC quickly gained prominence as an excipient—an inactive substance used as a carrier for the active ingredients of medications. Its unique properties, such as high water solubility and the ability to form viscous solutions, made it an ideal thickening and stabilizing agent in liquid medicines, syrups, and suspensions. Over the decades, CMC has been widely incorporated into various remedies, including antacids and laxatives, providing consistent texture and improving the palatability of medicinal products.

Historically, sodium carboxymethyl cellulose has also played a supportive role in the formulation of herbal combinations. By acting as a binder and disintegrant in herbal tablets and capsules, CMC helps ensure uniformity and stability, enhancing the delivery and effectiveness of herbal remedies. Its non-toxic and hypoallergenic nature makes it compatible with a broad spectrum of botanical ingredients, allowing practitioners and manufacturers to develop reliable and appealing herbal products. In topical preparations, CMC's soothing and hydrating qualities have been utilized to create gels and ointments for skin conditions, leveraging its ability to retain moisture and promote a protective barrier.

Overall, sodium carboxymethyl cellulose has contributed significantly to both modern and traditional medicine. Its versatility, safety profile, and functional benefits have improved the efficacy and user experience of countless nutritional and herbal products, making it an indispensable component in medicinal and wellness formulations worldwide.

Traditional and scientific validation

Sodium carboxymethyl cellulose (CMC) is a cellulose-derived polysaccharide widely used as a food additive and stabilizer in nutritional products. Its history dates back to the early 20th century, when it was first synthesized and recognized for its unique ability to thicken and stabilize aqueous solutions. CMC is prized in the food industry for its capacity to improve texture, extend shelf life, and enhance the palatability of various products, including dairy alternatives, meal replacements, and liquid nutrition formulas.

From a scientific perspective, CMC is considered physiologically inert and is not digested or absorbed in the human gastrointestinal tract, thereby contributing to dietary fiber intake. Several studies have investigated its potential effects on satiety and glycemic response, with some suggesting that CMC can modestly slow gastric emptying and glucose absorption, which may be beneficial in blood sugar management. Additionally, its use in enteral nutrition has been associated with improved viscosity and reduced risk of separation or sedimentation, supporting better nutrient delivery for patients requiring tube feeding.

While CMC is generally recognized as safe (GRAS) by regulatory agencies such as the FDA, more research is needed to fully elucidate its long-term health effects, particularly concerning gut microbiota and metabolic outcomes. Nonetheless, its well-established functional properties, safety profile, and versatility have made sodium carboxymethyl cellulose a valuable component in the formulation of modern nutritional products, supporting texture, stability, and dietary fiber enrichment.

Sodium carboxymethyl cellulose is used for these health conditions

Wounds and Sores (Scientific)

This ingredient is used to support these body systems

None

Products containing sodium carboxymethyl cellulose

We currently have no products on Vitabase that contain this ingredient.

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