Other names for Sodium choleate

sodium choleate

Synopsis of Sodium choleate

History

Sodium choleate, a sodium salt of cholic acid derived from bile, has a rich history in medicinal applications, particularly for its role in supporting digestion and liver health. Traditionally, bile salts like sodium choleate were recognized for their remarkable ability to emulsify fats, facilitating their absorption and aiding individuals with compromised bile production. In the 19th and early 20th centuries, sodium choleate became a staple in remedies designed to alleviate digestive discomfort, such as indigestion, constipation, and bloating. Physicians frequently prescribed it to patients suffering from biliary insufficiency, gallbladder disorders, and even certain types of jaundice, appreciating its gentle yet effective support of the body’s natural digestive processes.

Historically, sodium choleate was also incorporated into various herbal combinations to potentiate the bioavailability of fat-soluble nutrients and herbal constituents. Combined with herbal extracts like artichoke, dandelion, or milk thistle, sodium choleate helped enhance the therapeutic action of these botanicals—synergistically supporting liver detoxification, bile flow, and overall digestive wellness. Its role in such combinations was not only to facilitate the absorption of herbal compounds but also to provide a harmonizing effect on the gastrointestinal system.

Today, sodium choleate continues to be valued in nutritional and therapeutic products due to its safety, efficacy, and versatility. Its contributions to digestive health, both as a standalone ingredient and in combination with herbal remedies, reflect a legacy of positive impact on well-being, making it a trusted component in modern formulations aimed at promoting optimal digestive and liver function.

Traditional and scientific validation

Sodium choleate, the sodium salt of cholic acid, is a naturally occurring bile acid derivative commonly used as an ingredient in nutritional products and pharmaceuticals. Historically, choleate and related bile salts have played a significant role in the understanding of fat digestion and absorption, with their physiological functions well-documented since the early 20th century. Bile salts, including sodium choleate, act as natural emulsifiers, facilitating the breakdown and absorption of dietary fats and fat-soluble vitamins in the small intestine.

Scientific research supports the use of sodium choleate as a solubilizing agent and absorption enhancer. In pharmaceutical formulations, sodium choleate has been used to improve the bioavailability of poorly soluble compounds, demonstrating its value in drug delivery systems. Clinical and preclinical studies have shown that bile salts can enhance the absorption of certain nutrients and drugs by modifying membrane permeability and forming micelles that encapsulate lipophilic substances.

While direct clinical studies of sodium choleate as an isolated nutritional supplement are limited, the broader body of evidence on bile salts suggests potential benefits in supporting digestive health and nutrient uptake, particularly in individuals with impaired bile production. Sodium choleate is generally recognized as safe when used in appropriate amounts, and its inclusion in nutritional products is supported by its physiological relevance and history of use.

Nonetheless, more targeted research is needed to fully elucidate the specific health benefits and optimal applications of sodium choleate in human nutrition. Overall, sodium choleate remains a valuable ingredient, contributing to improved solubility, absorption, and digestive efficiency in nutritional and pharmaceutical contexts.

This ingredient is used for these health conditions

None

Sodium choleate is used to support these body systems

Digestive System (Scientific)
Gall Bladder (Scientific)
Gastrointestinal Tract (Scientific)
Intestinal System (Scientific)
Small Intestines (Scientific)

Products containing Sodium choleate

We currently have no products on Vitabase that contain this ingredient.