Trans-pterostilbene

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Other names for trans-pterostilbene

Pterostilbene
Dimethylresveratrol
Blueberry Polyphenol

Synopsis of trans-pterostilbene

Trans-pterostilbene is a naturally occurring stilbenoid, a class of compounds structurally similar to resveratrol, which is found in various plants, particularly in blueberries, grapes, and red wine. Trans-pterostilbene is often considered a more bioavailable and potent form of resveratrol, meaning it is more easily absorbed and utilized by the body. It is known for its antioxidant, anti-inflammatory, and neuroprotective properties, and has been studied for its potential in promoting heart health, supporting cognitive function, and reducing the risk of chronic diseases.

Trans-pterostilbene is thought to work by activating sirtuins, which are proteins that regulate cellular processes like aging, DNA repair, and energy metabolism. It also promotes mitochondrial function and enhances fat metabolism, making it a subject of interest in anti-aging and metabolic health research. Studies have shown that trans-pterostilbene may help reduce oxidative stress, lower blood cholesterol, and improve insulin sensitivity, supporting its potential benefits for cardiovascular health and weight management.

Additionally, trans-pterostilbene has been investigated for its neuroprotective effects, particularly in the context of cognitive health. Research suggests that it may support brain function by protecting neurons from oxidative damage, inflammation, and age-related degeneration, making it a potential candidate for Alzheimer’s disease and neurodegenerative conditions.

Historical Use in Medicine:
While trans-pterostilbene itself has only been studied in more recent decades, its precursor, resveratrol, has a much longer history of use in traditional medicine. Resveratrol was used in ancient Greek and Chinese medicine, where grapes and wine were valued for their antioxidant and anti-inflammatory effects. The connection between grapes and longevity, particularly in regions where wine consumption was common, has long been recognized, though the specific active compound—resveratrol—was not identified until the 1990s.

Trans-pterostilbene, as a more potent form of resveratrol, has not traditionally been used in herbal medicine. However, blueberries, which contain trans-pterostilbene, have long been recognized for their health benefits in various cultures. Native American tribes, for example, utilized blueberries and other berries for their antioxidant and immune-supporting properties. These fruits were consumed for their ability to improve digestion, reduce inflammation, and enhance overall vitality.

In the modern era, the anti-aging and antioxidant properties of stilbenoids, including both resveratrol and trans-pterostilbene, have garnered significant interest in scientific research. Trans-pterostilbene, in particular, is being explored for its potential role in improving metabolic health, brain function, and cardiovascular health, with numerous studies supporting its longevity-promoting effects and its ability to mitigate age-related diseases.

Today, trans-pterostilbene is commonly used as a dietary supplement and is included in formulations aimed at promoting heart health, cognitive function, and weight management. It is often marketed for its anti-aging effects, with some studies suggesting that it may provide long-term protection against oxidative stress and inflammation.

Trans-pterostilbene is used for these health conditions

Aging (prevention) (Scientific)
Alzheimer's Disease (Scientific)
Cancer (natural therapy for) (Scientific)
Cancer (prevention) (Scientific)
Cardiovascular Disease (Scientific)
Cholesterol (high) (Scientific)
Diabetes (Scientific)
Fatty Liver Disease (Scientific)
Inflammation (Scientific)
Memory and Brain Function (Scientific)
Metabolic Syndrome (Scientific)
Triglycerides (high) (Scientific)

trans-pterostilbene is used to support these body systems

Arteries (Scientific)
Blood (Scientific)
Brain (Scientific)
Circulatory System (Scientific)
Heart (Scientific)
Mitochondria (Scientific)

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