Vitamin B9 (folic acid)
Other names for Vitamin B9 (folic acid)
coenzyme folic acid
controlled release citrate d-pteroylmonoglutamic acid
cultured folic acid
folacin
folate
folic acid
folic acid b-9
folic acid dicalcium phosphate
folic acid trituration
levomefolic acid
liposomal vitamin b9
organic folic acid
poten-zyme(r) foiic acid
poten-zyme(r) folic acid
pteroylglutamic acid
Synopsis of Vitamin B9 (folic acid)
History
Vitamin B9, commonly known as folic acid, has a rich history in medicinal and nutritional applications. Its importance first came to light in the 1930s when researchers noted that certain types of anemia, particularly among pregnant women, responded well to dietary interventions involving leafy greens and liver. This led to the discovery of folic acid in the late 1940s. Traditionally, remedies addressing fatigue, weakness, and poor growth often included foods rich in folate, reflecting early empirical recognition of its value.
Folic acid’s greatest contribution has been in maternal and fetal health. By the mid-20th century, it was established that adequate intake of folic acid during pregnancy significantly reduces the risk of neural tube defects in newborns. As a result, it became a cornerstone of prenatal vitamins and nutritional guidance worldwide. Its reputation for supporting cell growth and regeneration also made it a favored component in convalescence tonics and general restorative blends.
In herbal medicine, folic acid naturally occurs in numerous plant-based remedies, such as spinach, parsley, nettle, and alfalfa. These herbs are often combined in traditional formulas to combat anemia, boost energy, and promote vitality. Modern herbal supplements frequently blend folic acid-rich botanicals to synergize with other nutrients, enhancing overall well-being. The positive impact of folic acid is undeniable: it supports healthy blood formation, cognitive function, and cellular repair, making it an invaluable ally in nutritional and herbal therapies alike.
Traditional and scientific validation
Vitamin B9, commonly known as folic acid in its synthetic form, has a long history of use in nutritional products due to its essential role in human health. Discovered in the 1930s, folic acid rapidly gained recognition for its necessity in DNA synthesis, cell division, and amino acid metabolism. Early clinical research in the 1940s identified folic acid as a key nutrient for preventing anemia, especially in pregnant women, leading to its widespread inclusion in prenatal supplements.
The most significant scientific validation for folic acid supplementation emerged in the 1990s, when large-scale studies demonstrated its ability to dramatically reduce the risk of neural tube defects (NTDs) such as spina bifida and anencephaly in newborns. As a result, many countries mandated the fortification of certain foods with folic acid, leading to a significant decline in NTD incidence.
Beyond pregnancy, research has explored folic acid’s potential benefits for cardiovascular health, cognitive function, and even mood regulation. Some studies suggest that adequate folic acid intake may lower homocysteine levels, a risk factor for cardiovascular disease, but results have been mixed and further research is needed to establish definitive benefits in these areas.
Overall, while certain effects of folic acid supplementation—particularly for NTD prevention—are well-established, other potential benefits continue to be investigated. Its proven safety, affordability, and essential biological functions strongly support its ongoing use in nutritional products, particularly for women of childbearing age and populations at risk of deficiency.
Vitamin B9 (folic acid) is used for these health conditions
Anemia (Scientific)
Birth Defects (prevention) (Scientific)
Cancer Treatment (reducing side effects) (Scientific)
Depression (Scientific)
Infertility (Scientific)
Memory and Brain Function (Scientific)
Miscarriage (prevention) (Scientific)
Pregnancy (herbs and supplements for) (Scientific)
Vitamin B9 (folic acid) is used to support these body systems
Blood (Scientific)
Brain (Scientific)
Female Reproductive System (Scientific)
Immune System (Scientific)
Intestinal System (Scientific)
Liver (Scientific)
Reproductive System (Scientific)
Small Intestines (Scientific)
Uterus (Scientific)