L-glutamine

Other names
Synopsis
Uses: Health Conditions
Uses: Body Systems
Products

Other names

Free-Form L-Glutamine
Micronized L-Glutamine
Fermented L-Glutamine

Synopsis

L-Glutamine is a non-essential amino acid that plays a central role in protein synthesis and is one of the most abundant amino acids found in the human body, particularly in muscle tissue and the brain. It is a key player in cell metabolism, immune function, and intestinal health. L-glutamine is primarily known for its muscle recovery and gut-healing properties, but it also supports brain function and cognitive health.

L-glutamine is involved in several essential functions:

Protein synthesis: It is a building block for proteins, supporting muscle repair and growth.
Gut health: L-glutamine serves as a fuel source for the cells of the intestinal lining and is crucial for maintaining the integrity of the gut. It helps in gut repair, preventing intestinal permeability (often referred to as leaky gut).
Immune function: L-glutamine is involved in the synthesis of immune cells and supports the immune system by providing energy to rapidly dividing immune cells during stress or illness.
Brain health: As a precursor to neurotransmitters such as glutamate, L-glutamine is important for cognitive function and the balance of excitatory signals in the brain.

L-glutamine is often taken in supplement form by athletes, bodybuilders, and individuals recovering from surgery, illness, or intense physical activity due to its role in muscle recovery, gut health, and immune support.

Historical Use
L-glutamine has been studied and recognized for its health benefits for decades. In the early 20th century, it was first identified as an amino acid with the capacity to support protein synthesis and cellular metabolism. However, its broader role in gut health and immune function wasn’t fully appreciated until more recent research.

In clinical nutrition, L-glutamine has been used as a therapeutic agent for critical illness or trauma, especially in patients recovering from surgery or burns, to promote intestinal healing, muscle preservation, and immune system support. Over time, its popularity in sports nutrition grew as it was recognized for its potential to support muscle recovery and reduce exercise-induced muscle soreness.

Modern Use
L-glutamine is widely used in sports nutrition and supplements aimed at improving exercise performance and muscle recovery. It is also a common ingredient in gut health supplements due to its role in maintaining the intestinal barrier and gut integrity. Some common uses of L-glutamine include:

Muscle recovery: L-glutamine helps reduce muscle soreness, improves muscle repair, and supports muscle growth, especially after intense exercise.
Gut health: L-glutamine is often used to help heal the intestinal lining, support digestive function, and prevent intestinal permeability. It is commonly included in leaky gut protocols and gut-healing supplements.
Immune support: L-glutamine is used to enhance immune function, particularly in individuals who are recovering from illness, injury, or intense physical stress.
Cognitive support: As a precursor to glutamate, L-glutamine may help with brain function, supporting mental clarity, focus, and memory.

L-glutamine is typically available in powder, capsule, or tablet form, and is often taken in doses ranging from 5 to 10 grams per day, depending on individual needs and goals. It is commonly found in pre-workout, post-workout, and gut health supplements.

Safety Considerations
L-glutamine is generally considered safe when used as directed, with minimal side effects. However, high doses (above 40 grams per day) may cause gastrointestinal discomfort, including bloating or diarrhea. Individuals with kidney or liver conditions should consult with a healthcare provider before using L-glutamine supplements. Pregnant and breastfeeding women should also seek medical advice before starting supplementation.

Uses: Health Conditions

Celiac Disease (Traditional)
Chemotherapy (reducing side effects) (Traditional)
Endurance (lack of) (Traditional)
Energy (lack of) (Traditional)
Exercise (Traditional)
Fat Cravings (Traditional)
Fatigue (Traditional)
Fibromyalgia Syndrome (Traditional)
Leaky Gut Syndrome (Traditional)

Body Systems

Brain (Traditional)
Intestinal System (Traditional)
Nerves (Traditional)

Products containing this ingredient

Health Concerns

Brands