Lactobacillus jensenii

Other names

L. jensenii
Probiotic Vaginal Strain
Human-Origin Lactobacillus

Synopsis

Lactobacillus jensenii is a species of lactic acid bacteria that resides predominantly in the female urogenital tract. It is considered one of the most protective members of the vaginal microbiota, contributing to a healthy microbial balance by producing lactic acid and hydrogen peroxide (H₂O₂), which help maintain an acidic pH and suppress the growth of pathogenic organisms such as Gardnerella vaginalis, Candida albicans, and Escherichia coli. This creates a stable, inhospitable environment for opportunistic infections and supports vaginal immunity.

Modern research highlights L. jensenii as an essential biomarker for vaginal health. Its dominance is often associated with reduced risk of bacterial vaginosis (BV), urinary tract infections (UTIs), sexually transmitted infections (STIs), and even complications during pregnancy. Unlike more generalized probiotic strains, L. jensenii is often featured in targeted women’s health probiotic formulations, sometimes delivered intravaginally. It adheres well to vaginal epithelial cells, competitively excludes pathogens, and contributes to mucosal immune regulation.

Because of its role in maintaining urogenital health, L. jensenii is increasingly being studied for potential therapeutic use in fertility, postpartum care, and menopausal vaginal atrophy.

Historical Use:
Though Lactobacillus jensenii was identified only in the mid-20th century, the health benefits linked to its presence have been indirectly recognized for centuries through traditional approaches to women’s reproductive and urinary tract care. Historical and folk medicine systems routinely emphasized the importance of internal balance, hygiene, and immune resilience in the female body, often recommending plant-based vaginal steams, herbal infusions, and fermented milk products to support reproductive health.

In many traditional cultures, fermented dairy and vegetable foods were consumed regularly and were likely supportive of overall microbiome health, including the vaginal ecosystem. Though the concept of probiotic microbes was unknown, the general practice of using sour milk, yogurt, or even topical poultices for urogenital complaints can be viewed as crude but functionally effective prebiotics and probiotics in action.

More broadly, in Greco-Arabic medicine and traditional European herbalism, treatments for what we now recognize as bacterial vaginosis or candidiasis often involved restoring internal harmony and acidifying the vaginal tract—aims that L. jensenii naturally fulfills.

Today, thanks to molecular and genomic research, we understand that L. jensenii is not only a benign commensal but also a protective species critical to the health of the vaginal microbiome. Its inclusion in women’s probiotic therapies reflects a sophisticated evolution of age-old practices, updated with modern scientific insight.

Uses: Health Conditions

Urinary Tract Infections (Scientific)
Vaginitis (Scientific)

Body Systems

Female Reproductive System (Science)
Immune System (Science)
Intestinal System (Science)
Urinary System (Science)
Digestive System (Traditional)
Gastrointestinal Tract (Traditional)
Large Intestines (Colon) (Traditional)
Mucus Membranes (Traditional)
Reproductive System (Traditional)
Small Intestines (Traditional)
Vagina (Traditional)
Peyer’s patches (Traditional)