Currently there is no data to suggest that biotin supplementation negatively interacts with Oral Birth Control Pills. Most of the research actually suggests the opposite. Certain B-vitamins are known to be depleted by long term use of birth control pills and it is often suggested that women supplement with these nutrients to avoid potentially harmful deficiencies. In fact, a pharmaceutical company released a prescription vitamin/mineral supplement in 2004 specifically for women on the birth control pill to address this aspect of nutrient depletion from long term use. Biotin was included in that formula.
Also of particular concern regarding nutrient depletion from long term use of the oral birth control pill is folic acid and vitamin B6.