Evidence supporting the use of: Asiaticoside
For the health condition: Abrasions

Links: Go back one page, Tool main page, Ingredients list, Health conditions list, Body systems list

Synopsis

Source of validity: Scientific
Rating (out of 5): 3

Asiaticoside for Abrasions: Evidence Synopsis

Asiaticoside is a triterpenoid saponin compound extracted from Centella asiatica, a medicinal plant used in traditional medicine for wound healing. Its application for abrasions is supported by both historical use and scientific investigations, with the strongest validation arising from modern studies.

Preclinical research demonstrates that asiaticoside can promote wound healing by stimulating collagen synthesis and angiogenesis. Multiple in vitro and in vivo studies have shown that asiaticoside enhances proliferation and migration of fibroblasts and keratinocytes, which are crucial for the repair of superficial skin injuries such as abrasions. It also modulates inflammatory cytokines, leading to a more favorable environment for tissue regeneration.

Animal studies, including those using excisional and abrasion wound models, report accelerated wound closure and improved histological features in wounds treated with asiaticoside compared to controls. While there are several animal and cell culture studies, high-quality randomized clinical trials in humans are relatively limited. Nonetheless, some topical formulations containing asiaticoside (alone or with other Centella asiatica components) have been used in clinical practice for minor wounds, showing favorable outcomes and safety profiles.

Overall, the evidence for asiaticoside in supporting the healing of abrasions is promising and grounded in scientific research, although the clinical evidence is not yet robust enough to warrant the highest rating.

More about Asiaticoside
More about Abrasions

Products containing Asiaticoside

We currently have no products on Vitabase that contain this ingredient.