Centella triterpenes, the primary active compounds in Centella asiatica (commonly known as Gotu Kola), have a long-standing traditional use in wound healing, including abrasions. More importantly, there is moderate scientific evidence supporting their efficacy in this context. The triterpene constituents—such as asiaticoside, madecassoside, asiatic acid, and madecassic acid—are recognized for promoting collagen synthesis, stimulating fibroblast proliferation, and enhancing angiogenesis, all of which are critical for effective wound healing.

Several in vitro and animal studies have demonstrated that Centella triterpenes can accelerate wound closure, increase tensile strength of the skin, and improve re-epithelialization. For example, research published in the Journal of Ethnopharmacology (2006) and Planta Medica (1999) showed enhanced wound contraction and faster healing in treated groups compared to controls. Clinical studies are fewer but suggest Centella preparations may reduce healing time and improve scar quality in minor wounds and abrasions.

However, while promising, much of the evidence is preclinical or based on small-scale clinical trials, leading to a moderate evidence rating. Larger, well-controlled human studies are needed to fully establish efficacy and safety for the routine treatment of abrasions.