Common Plantain (Plantago major) has a long history of traditional use in treating minor wounds and abrasions, but there is also some scientific evidence supporting its efficacy. The leaves contain bioactive compounds such as allantoin, aucubin, and various flavonoids, which have demonstrated anti-inflammatory, antimicrobial, and wound-healing properties in laboratory studies. These constituents are believed to promote tissue regeneration and reduce the risk of infection when applied topically.

Several in vitro and animal studies have shown that extracts of Plantago major can accelerate wound closure, decrease inflammation, and inhibit the growth of some pathogenic bacteria. For example, a study published in the journal Phytotherapy Research demonstrated that ointments containing Plantago major extract increased the rate of healing in experimentally induced wounds in rats compared to controls.

However, while the laboratory and animal evidence is promising, there are limited well-controlled human clinical trials specifically examining the effect of Plantain on abrasions. Most human reports are anecdotal or based on traditional use. Therefore, while scientific research provides a plausible rationale and some experimental validation, more rigorous human studies are needed to fully confirm its efficacy for treating abrasions.