Evidence supporting the use of: Iridoid glycosides
For the health condition: Abrasions
Synopsis
Source of validity: Traditional
Rating (out of 5): 2
Iridoid glycosides are a group of phytochemicals commonly found in medicinal plants such as Plantago species (plantain), Harpagophytum procumbens (devil’s claw), and Scrophularia species. Their use in supporting or treating abrasions is primarily grounded in traditional herbal medicine practices. For instance, Plantago major leaves, rich in iridoid glycosides like aucubin and catalpol, have been used as poultices or topical applications for wounds, minor cuts, and abrasions in various cultures. The rationale is based on observed anti-inflammatory, antimicrobial, and wound-healing properties attributed to the whole plant or extracts.
While some in vitro and animal studies suggest that iridoid glycosides may promote wound healing by enhancing collagen synthesis, reducing inflammation, and providing antimicrobial effects, direct clinical evidence in humans for their use specifically in abrasions is limited. Most of the support comes from ethnobotanical records and historical use, rather than from rigorous clinical trials. Therefore, the traditional use is relatively well-documented, but scientific validation remains preliminary and indirect.
In summary, iridoid glycosides are used to support the healing of abrasions mainly due to a strong tradition of use in herbal medicine, with moderate preclinical support but lacking robust clinical evidence specific to abrasions.
Other ingredients used for Abrasions
aloe verabeeswax
bisabolol
chamomile
turmeric
glycerin
goldenseal
gotu kola
hyaluronic acid
lavender
licorice root
microbial enzymes (proprietary)
mucin
plantain
protease
purified silver
slippery elm bark
vitamin C
zinc
chickweed
xanthium (cockleburs)
shen-chu
nut grass
clerodendrum indicum
paederia foetida
boxthorne
yarrow
moss
myrrh
siler root
oriental arborvitae
assam indigo
paw paw
white oak
melaleuca alternifolia
geranium
arnica
sea salt
Ash
Avens
Asiaticoside
acacia
Agave
Agrimony
Antirrhinum majus
Achyranthes
Anamu
Abrus
Alchornea
Alchemilla
Ajuga
Aquilegia formosa
Allantoin
Alkanet
Alsonia scholaris
Ampelopsis
Abuta
Alkanna
Bee Propolis
Bai Ji
Blackthorn
Balsam
Blackbrush
Butea monosperma
Barleria
Brazillian peppertree
Bee hive
Bloodroot
Benzoin
Banyan
Bletilla
Bee products
Bombax
Boerhavia diffusa
Calochortus
Comfrey
Centella triterpenes
Calendula
Calotropis gigantea
Colloidal Silver
Capillary Artemisia
Cinquefoil
Cattail
Cocoa Butter
Cymbidium goeringii
Cornflower
Cowherb
Centella asiatica
Celandine
Centipeda
Carrapichinho
Cedrus libani
Castile Soap
Cynodon dactylon
Cocklebur
Cynanchum
Casearia sylvestris
Didymocarpus
Dragon's Blood
Davilla rugosa
Epidermal Growth Factor
Erigeron
Elephant Vine
Erodium cicutarium
English Elm
Elephant's Head
Euphorbia
fibroblast growth factor
Little ironweed
Oak
Polyvinyl alcohol
Other health conditions supported by Iridoid glycosides
Abdominal PainAbrasions
Arthritis
Asthma
Backache
Bronchitis
Bruises (healing)
Burns and Scalds
Canker Sores
Colds (general)
Cuts
Dermatitis
Diabetes
Diarrhea
Dyspepsia
Eczema
Fatigue
Fever
Gastritis
Gingivitis
Inflammation
Injuries
Jaundice (adults)
Pain (general remedies for)