Evidence supporting the use of: Panthenol
For the health condition: Abrasions

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Synopsis

Source of validity: Scientific
Rating (out of 5): 3

Panthenol, also known as provitamin B5, is commonly used in topical formulations for skin abrasions due to its hydrating and barrier-supporting properties. Scientific evidence indicates that panthenol promotes wound healing, primarily by enhancing fibroblast proliferation, supporting epithelialization, and maintaining skin hydration, which are essential for effective repair of superficial wounds like abrasions.

Several in vitro and in vivo studies have demonstrated that panthenol can accelerate the closure of minor wounds and abrasions. For example, clinical trials have shown that topical panthenol leads to improved stratum corneum hydration and a reduction in skin irritation, which may indirectly facilitate faster healing of abrasions. A randomized controlled trial published in Cutaneous and Ocular Toxicology (2014) found that a dexpanthenol-containing ointment significantly improved wound healing compared to placebo in patients with superficial skin injuries.

While panthenol is not considered a primary wound-healing agent like some advanced dressings or prescription medications, its favorable safety profile and evidence of supporting re-epithelialization and reducing transepidermal water loss make it a scientifically justified supportive treatment for minor abrasions. However, the strength of evidence is moderate (rated 3/5), as most studies are small or focus on surrogate markers such as hydration and irritation rather than hard clinical outcomes.

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Products containing Panthenol

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