Petroleum jelly, commonly known as petrolatum, is scientifically validated for use in the management of abrasions and minor wounds. Its primary role is as an occlusive moisturizer that forms a protective barrier over the skin, reducing transepidermal water loss and maintaining a moist wound environment. Clinical studies and dermatological guidelines support the use of petroleum jelly to aid in wound healing by preventing the wound from drying out and forming a hard scab, which can delay healing and increase the risk of scarring. The American Academy of Dermatology and other professional bodies recommend applying petroleum jelly to clean, minor wounds, including abrasions, to expedite healing and minimize scar formation.

Unlike topical antibiotics, which may contribute to antibiotic resistance or allergic reactions, petroleum jelly is inert, rarely causes irritation, and has a well-established safety profile. Several randomized controlled trials and reviews have demonstrated that petroleum jelly is as effective as, or even superior to, antibiotic ointments for uncomplicated superficial wounds in terms of healing time and infection prevention. Its use is thus grounded in both clinical evidence and standard medical practice, making it a scientifically supported treatment option for abrasions.