Evidence supporting the use of: Transforming growth factor beta
For the health condition: Abrasions

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Synopsis

Source of validity: Scientific
Rating (out of 5): 4

Transforming growth factor beta (TGF-β) is justified for use in supporting or treating abrasions based on scientific evidence. TGF-β is a multifunctional cytokine that plays a pivotal role in wound healing, including the repair of skin abrasions. Scientific studies have demonstrated that TGF-β modulates inflammation, stimulates fibroblast proliferation, enhances collagen synthesis, and promotes re-epithelialization—key processes in wound repair. Experimental models, including animal studies and in vitro assays, have shown that application of TGF-β accelerates closure of abrasions and improves the quality of healing tissue. Furthermore, TGF-β is involved in the recruitment of immune cells and regulation of extracellular matrix production, both vital for effective tissue regeneration. However, while preclinical data are robust, clinical trials in humans are relatively limited, often due to concerns about excessive scarring or fibrosis with unregulated TGF-β activity. Some wound care products and experimental therapies incorporate TGF-β or its analogs to leverage these healing properties. In summary, the use of TGF-β for treating abrasions is supported by substantial mechanistic and experimental evidence, though more clinical research is warranted to optimize its therapeutic application and mitigate potential adverse effects such as hypertrophic scarring.

More about Transforming growth factor beta
More about Abrasions

Other ingredients used for Abrasions

Aloe vera
beeswax
bisabolol
chamomile
turmeric
glycerin
goldenseal
gotu kola
hyaluronic acid
lavender
licorice root
microbial enzymes (proprietary)
mucin
plantain
protease
purified silver
slippery elm bark
vitamin C
zinc
chickweed
xanthium (cockleburs)
shen-chu
nut grass
clerodendrum indicum
paederia foetida
boxthorne
yarrow
moss
myrrh
siler root
oriental arborvitae
assam indigo
paw paw
white oak
melaleuca alternifolia
geranium
arnica
impatiens
sea salt
Ash
Avens
Asiaticoside
Acacia
Agave
Agrimony
Antirrhinum majus
Achyranthes
Anamu
Abrus
Alchornea
Alchemilla
Ajuga
Aquilegia formosa
Allantoin
Alkanet
Alsonia scholaris
Ampelopsis
Abuta
Alkanna
Bee Propolis
Bai Ji
Blackthorn
Balsam
Blackbrush
Butea monosperma
Barleria
Brazilian peppertree
Bee hive
Bloodroot
Benzoin
Bindweed
Banyan
Bletilla
Bee products
Bombax
Boerhavia diffusa
Calochortus
Comfrey
Centella triterpenes
Calendula
Calotropis gigantea
Colloidal Silver
Capillary Artemisia
Cinquefoil
Cattail
Cocoa Butter
Cymbidium goeringii
Cornflower
Cowherb
Centella asiatica
Celandine
Centipeda
Carrapichinho
Cedrus libani
Castile Soap
Cynodon dactylon
Cocklebur
Cynanchum
Casearia sylvestris
Didymocarpus
Dragon's Blood
Davilla rugosa
Epidermal Growth Factor
Erigeron
Elephant Vine
Erodium cicutarium
English Elm
Elephant's Head
Euphorbia
Flueggea suffruticosa
Fomes fomentarius
Ficin
Fibrinase
fibroblast growth factor
Fir
Genipap
Gnaphalium
Gambir
Growth factors
Genipa americana
Gugambilla
Golden Shower Tree
Honey
Heal-All
Hydrocolloid
Henna
Iridoid glycosides
Immortelle
Jojoba Oil
Jessica's Sticktight
Kigelia africana
Kalanchoe pinnatum
Lacquertree
Lesser speargrass
Lilium polyphyllum
Lophira lanceolata
Lodhtree
lac resin
Lygodium
Lantana camara
Leptospermum scoparium
Little ironweed
Maritime Dock
Mountain horopito
Malva sylvestris
Matico
Mahonia
Milkweed
Marigold
Marking Nut Tree
Macaranga indica
Nimbidin
Oak
Oxystelma
Propolis
Purple Tephrosia
Povidone
Plantago
Panthenol
Plumbago zeylanica
Prolase
Red Alder
Resin
Red Spiderling
Rosa californica
Rhus glabra
Sanicle
Sesbania
Speedwell
Spanish Needle
Sausage Tree
Silverweed
Shikonin
Self-Heal
Smooth Alder
Sensitive Plant
Sericin
Sanguisorba
Sickle-leaf hare's ear
Stellaria dichotoma
Sapindus mukorossi
Stereospermum
Smoketree
Trumpet Vine
Tannins
Tridax
Thymol
Tea Tree Oil
Tagetes
Whiteweed
Witch Hazel
Waltheria ovata
Yerba Mansa

Products containing Transforming growth factor beta

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