Plectranthus amboinicus, commonly known as Indian borage or Cuban oregano, is traditionally used in various cultures for the treatment of abscesses and other skin infections. Ethnobotanical records from regions such as India, Africa, and Southeast Asia document the use of crushed leaves or poultices applied topically to abscesses, boils, and similar suppurative skin conditions. The justification for this use primarily stems from folk medicine and the empirical knowledge passed down through generations. Traditional healers often attribute the healing effects to the plant’s aromatic oils and perceived antimicrobial properties.

Scientific evidence supporting the topical use of P. amboinicus specifically for abscesses is limited. Some in vitro studies have demonstrated that extracts of the plant possess antibacterial activity against certain pathogens, including Staphylococcus aureus, which is commonly implicated in abscesses. However, these studies are preliminary and do not directly confirm clinical efficacy in treating abscesses in humans. No rigorous clinical trials or systematic reviews currently validate its effectiveness for this condition. Therefore, while traditional use is well-documented, scientific validation remains insufficient and the overall evidence rating is low.