Sangre de Grado (also known as Dragon's Blood, derived from the sap of the Croton lechleri tree) has a long history of traditional use in South American medicine, particularly among indigenous populations in the Amazon basin. It is commonly applied topically to wounds, ulcers, and abscesses to promote healing and prevent infection. The traditional rationale is based on the resin's perceived ability to form a protective barrier, staunch bleeding, and accelerate tissue regeneration.

Scientific studies have demonstrated that Sangre de Grado contains compounds such as proanthocyanidins and taspine, which exhibit antimicrobial, anti-inflammatory, and wound-healing properties. However, the majority of available research has focused on its efficacy in promoting wound healing and treating ulcers, rather than directly targeting abscesses. An abscess, being a localized collection of pus caused by infection, typically requires antimicrobial action and sometimes drainage. While in vitro studies suggest that Sangre de Grado has some antibacterial activity, robust clinical data supporting its use specifically for abscesses is lacking. The use of Sangre de Grado for abscesses remains rooted primarily in traditional practice, with only preliminary scientific evidence suggesting potential benefits. Medical standards of care for abscesses still rely on drainage and systemic antibiotics when needed.