The use of Sesbania species, particularly Sesbania grandiflora, for treating abscesses is primarily rooted in traditional medicine systems. Ethnobotanical surveys in regions of South and Southeast Asia have documented the topical application of Sesbania leaf or flower pastes for skin infections, boils, and abscesses. The rationale in folk medicine is often attributed to the plant's presumed anti-inflammatory and antimicrobial properties. However, while some laboratory studies have indicated that extracts from Sesbania species may possess mild antibacterial activity, there are no robust clinical or preclinical studies specifically validating its efficacy for abscess treatment in humans.

The available scientific literature consists mainly of in vitro antimicrobial assays, which are preliminary and do not equate to clinical effectiveness. No randomized controlled trials, animal studies on abscesses, or pharmacological investigations have been specifically conducted to assess the safety or therapeutic benefit of Sesbania for abscesses. Thus, while its use is well-documented in traditional medicine, scientific evidence supporting these traditional claims remains very limited. The evidence rating is therefore low, reflecting the gap between traditional use and scientific validation.