Evidence supporting the use of: Bacopa glycoside (unspecified)
For the body system: Acetylcholine

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Table of Contents

Synopsis

Source of validity: Scientific
Rating (out of 5): 3

Bacopa monnieri, commonly known as Brahmi, contains active compounds known as bacopa glycosides (often referred to as bacosides). It has a long history of traditional use in Ayurveda as a cognitive enhancer, but there is also a growing body of scientific research exploring its effects on the cholinergic system, which uses acetylcholine as its primary neurotransmitter. Several preclinical studies suggest that bacopa extracts and bacosides may enhance cholinergic function by increasing acetylcholine levels, upregulating choline acetyltransferase (the enzyme responsible for acetylcholine synthesis), and inhibiting acetylcholinesterase, the enzyme that degrades acetylcholine. These mechanisms are thought to underlie improvements in memory and cognitive performance observed in animal models.

In human clinical trials, Bacopa monnieri supplementation has been shown to improve aspects of memory, attention, and cognitive processing, although the exact link to acetylcholine modulation in humans is less directly established. Nevertheless, the evidence suggests that bacopa glycosides do interact with the acetylcholine system, supporting their use for cognitive health and memory. However, more robust, large-scale clinical trials are needed to confirm the specific impact on the acetylcholine system and the degree of benefit in humans.

Overall, the use of Bacopa glycosides to support the acetylcholine body system is supported by both traditional use and emerging scientific research, with moderate evidence (rated 3 out of 5) for their efficacy in modulating cholinergic neurotransmission and supporting cognitive function.

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Other body systems supported by Bacopa glycoside (unspecified)

Acetylcholine
Brain
Nerves
Parasympathetic Nervous System
Specific Neurotransmitters

Products containing Bacopa glycoside (unspecified)

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