Evidence supporting the use of: Eria
For the body system: Acetylcholine
Synopsis
Source of validity: Scientific
Rating (out of 5): 2
Eria jarensis is a plant whose extract is sometimes used in nootropic and pre-workout supplements, primarily due to the presence of N-phenethyl dimethylamine (NPDMA), a compound structurally similar to phenylethylamine (PEA). The rationale for its use in supporting the acetylcholine system is based largely on its purported stimulant and neuromodulatory effects. However, direct scientific research on Eria jarensis and its specific impact on the acetylcholine system in humans is limited. There are some animal and in vitro studies that suggest phenethylamine derivatives can influence neurotransmitter levels, including acetylcholine, but these effects are not well-characterized or confirmed in clinical trials for Eria jarensis specifically.
Most evidence for its cognitive effects comes from its structural similarity to other compounds known to affect neurotransmitters rather than from robust pharmacological studies. The ingredient is more commonly discussed for its potential to support mood and focus via dopaminergic and noradrenergic pathways, rather than directly enhancing acetylcholine. Thus, while there is some preliminary scientific rationale and anecdotal support, the overall evidence for Eria jarensis as a direct acetylcholine support ingredient is weak. More research is needed to clarify its effects and mechanisms of action in humans.
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