Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Lactiplantibacillus plantarum is a well-studied probiotic bacterium, commonly found in fermented foods and used as a dietary supplement. Its use for acid indigestion (also known as dyspepsia or functional dyspepsia) is justified to a modest extent by scientific evidence, though the level of evidence is not robust. Several clinical studies suggest that L. plantarum can promote gut health by modulating the gut microbiota, reducing inflammation, and enhancing the function of the intestinal barrier. These mechanisms may indirectly help alleviate symptoms related to acid indigestion, such as bloating, discomfort, and irregular digestion. For instance, small-scale studies and pilot trials have shown that L. plantarum supplementation can improve overall gastrointestinal comfort and reduce symptoms of indigestion in some subjects.

However, while there is some scientific rationale and a handful of supportive studies, large-scale, high-quality randomized controlled trials specifically targeting acid indigestion are lacking. Most evidence comes from studies assessing general digestive health or irritable bowel syndrome, with acid indigestion often reported as a secondary outcome. The American Gastroenterological Association and similar bodies recognize the potential of probiotics like L. plantarum for digestive health, but do not specifically endorse their use for acid indigestion due to insufficient conclusive data. In summary, L. plantarum shows promise for supporting digestive comfort, including acid indigestion, but more targeted research is needed to fully validate its efficacy for this specific condition.

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