Evidence supporting the use of: Allantoin
For the health condition: Acne

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Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Allantoin is a compound commonly used in skincare products due to its soothing, moisturizing, and keratolytic (skin-softening and exfoliating) properties. There is some scientific basis for its use in the management of acne, though evidence is limited and not robust. The primary rationale comes from allantoin’s ability to promote the shedding of dead skin cells (keratolysis), which can help prevent clogged pores—a contributing factor in acne formation. Additionally, allantoin is known for its anti-irritant and skin-calming effects, making it beneficial in reducing redness and irritation that often accompany acne lesions or the use of harsher anti-acne medications like benzoyl peroxide or retinoids.

However, the direct evidence supporting allantoin as an active treatment for acne is weak. Most studies focus on its general skin benefits such as wound healing, moisturizing, and reducing irritation, rather than on its independent efficacy against acne. It is often included in acne formulations more for its supportive role—alleviating irritation and enhancing skin barrier repair—rather than as a primary anti-acne agent. In summary, while allantoin has some scientifically supported skin benefits relevant to acne-prone skin, there is limited direct clinical evidence supporting its use as a standalone treatment for acne.

More about Allantoin
More about Acne

Other ingredients used for Acne

15,16-Dihydrotanshinone I
Abrus
Ajoene
Allantoin
Allicin
Aloe vera
Alpha hydroxy acids
alpha-pinene
alpha-terpineol
andrographolide
Anemarrhena
anemarrhena asphodeloides
apple cider vinegar
argan nut oil
ash
Asteraceae
azelaic acid
babchi
banyan
Baphicacanthus cusia
Bassia scoparia
bee products
bee propolis
berberine
Bidens pilosa
black cumin
black seed
blackboard tree
burdock
bасора
Calendula
cannabichromene
cannabigerol
Cannabis sativa oil
carvacrol
caryophyllene
castile soap
Centipeda
chamomile
chinatree
Chinese raisintree
chlorophyllin
chrysanthemum
Clerodendrum indicum
coconut
copaiba oil
cucumber
Curcuma
curcumen
curcumin
Curcuminoid
Dianthus
DIM (diindolylmethane)
Eclipta
epigallocatechin gallate (EGCG)
essential oil blend
estrogen
ethyl linoleate
eugenol
evening primrose oil
evening primrose oil
fatty acids
fulvic acid
gallic acid
garlic bulb
Glabridin
glyceryl monolaurate
Glycolic acid
green tea
heal-all
hemp
hemp oil
henna
herbal blend (proprietary)
Himalaya berry
honey
honeysuckle
Hydrocolloid
Immortelle
Indian fagonia
indigo leaves
Isatis
jojoba oil
Kigelia africana
Kokilaksha
L-cystine
Labdanum
lactic acid
Lactobacillus
Lactobacillus acidophilus
Lactobacillus casei
Lactobacillus plantarum
Lactobacillus reuteri
Lactobacillus rhamnosus
Lactoperoxidase
lauric acid
lavender
licorice root
Litsea
Mahonia
mangostin
Marking Nut Tree
melaleuca alternifolia
Melia
Momordica
Monolaurin
Monoterpenes
Morinda
Neem tree
Niacinamide (vitamin B3)
Nigella seed
omega-3 fatty acids
omega-6 fatty acids
oregon grape
oriental arborvitae
paederia foetida
Pansit-pansitan
pantothenic acid (vitamin B5)
Pentacyclic triterpenoids
Peptides
phenolic compounds
phlorotannins
probiotics
Propolis
scrophularia root
seaweed
Self-Heal
Sesquiterpenes
shen-chu
Shikonin
Smoketree
Soapberry
Sophora
Sphaeranthus indicus
Stellaria dichotoma
Tagetes
Tea Tree Oil
Terpenoids
Terpinen-4-ol
thyme
Thymol
Thymoquinone
Tinospora cordifolia
trace minerals
Triterpenes
turmeric
Viola
Violet
vitamin A
vitamin B
vitamin C
vitamin D
vitamin E
White Tea
Witch Hazel
Wrightia tinctoria
Xanthorrhizol
Zinc

Products containing Allantoin

We currently have no products on Vitabase that contain this ingredient.