Evidence supporting the use of: Cannabigerol
For the health condition: Acne
Synopsis
Source of validity: Scientific
Rating (out of 5): 2
Cannabigerol (CBG) is a non-psychoactive cannabinoid found in the Cannabis sativa plant. Its use for acne is primarily supported by preliminary scientific studies, rather than traditional use or robust clinical evidence. The scientific rationale for CBG in acne management is based on its anti-inflammatory and antibacterial properties, demonstrated in preclinical models. A 2016 study published in Experimental Dermatology indicated that CBG, like other cannabinoids, can inhibit lipogenesis in human sebocytes, which may help reduce excessive sebum production—a key factor in acne development. Additional in vitro research has shown that CBG exhibits antibacterial activity, including against Propionibacterium acnes (now known as Cutibacterium acnes), the bacteria implicated in acne pathogenesis. However, clinical trials in humans are lacking, and most available data are from laboratory or animal studies. Thus, while there is a scientific basis for considering CBG as a potential acne treatment, the evidence is limited and not yet conclusive. No traditional or historical records support the use of CBG specifically for acne, as its isolation and study are relatively recent. Further research, particularly well-designed human studies, is needed to establish efficacy, safety, and optimal usage protocols for CBG in acne management.
Other ingredients used for Acne
15,16-Dihydrotanshinone IAbrus
Ajoene
Allantoin
Allicin
Aloe vera
Alpha hydroxy acids
alpha-pinene
alpha-terpineol
andrographolide
Anemarrhena
anemarrhena asphodeloides
apple cider vinegar
argan nut oil
ash
Asteraceae
azelaic acid
babchi
banyan
Baphicacanthus cusia
Bassia scoparia
bee products
bee propolis
berberine
Bidens pilosa
black cumin
black seed
blackboard tree
burdock
bасора
Calendula
cannabichromene
cannabigerol
Cannabis sativa oil
carvacrol
caryophyllene
castile soap
Centipeda
chamomile
chinatree
Chinese raisintree
chlorophyllin
chrysanthemum
Clerodendrum indicum
coconut
copaiba oil
cucumber
Curcuma
curcumen
curcumin
Curcuminoid
Dianthus
DIM (diindolylmethane)
Eclipta
epigallocatechin gallate (EGCG)
essential oil blend
estrogen
ethyl linoleate
eugenol
evening primrose oil
evening primrose oil
fatty acids
fulvic acid
gallic acid
garlic bulb
Glabridin
glyceryl monolaurate
Glycolic acid
green tea
heal-all
hemp
hemp oil
henna
herbal blend (proprietary)
Himalaya berry
honey
honeysuckle
Hydrocolloid
Immortelle
Indian fagonia
indigo leaves
Isatis
jojoba oil
Kigelia africana
Kokilaksha
L-cystine
Labdanum
lactic acid
Lactobacillus
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Lactobacillus casei
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Lactoperoxidase
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Litsea
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Niacinamide (vitamin B3)
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oregon grape
oriental arborvitae
paederia foetida
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Pentacyclic triterpenoids
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White Tea
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Xanthorrhizol
Zinc