Evidence supporting the use of: Ethyl linoleate
For the health condition: Acne
Synopsis
Source of validity: Scientific
Rating (out of 5): 3
Ethyl linoleate is an ester of linoleic acid, a polyunsaturated fatty acid known to play a role in skin health. Scientific research suggests that topical linoleic acid and its derivatives, including ethyl linoleate, may benefit acne-prone skin. Studies have found that individuals with acne have lower levels of linoleic acid in their skin surface lipids, which is thought to contribute to follicular hyperkeratosis and comedone formation. Supplementing the skin with linoleic acid derivatives may help restore the lipid barrier, reduce inflammation, and normalize keratinization.
One published study ("Topical Ethyl Linoleate Reduces Inflammation in Acne Vulgaris") found that topical application of ethyl linoleate can inhibit the production of pro-inflammatory mediators in sebocytes, the cells that produce sebum. This suggests an anti-inflammatory effect relevant to acne pathology. Additionally, ethyl linoleate may reduce sebum production and help prevent the formation of comedones. However, while these mechanisms are supported by laboratory and some clinical data, large-scale human trials are limited, and the ingredient is more commonly found in cosmeceuticals than in pharmaceutical treatments for acne.
In summary, there is emerging scientific evidence supporting the use of ethyl linoleate in acne management, particularly due to its anti-inflammatory properties and its role in restoring deficient skin lipids. The evidence, however, is moderate and primarily based on mechanistic studies and smaller clinical trials.
Other ingredients used for Acne
15,16-Dihydrotanshinone IAbrus
Ajoene
Allantoin
Allicin
Aloe vera
Alpha hydroxy acids
alpha-pinene
alpha-terpineol
andrographolide
Anemarrhena
anemarrhena asphodeloides
apple cider vinegar
argan nut oil
ash
Asteraceae
azelaic acid
babchi
banyan
Baphicacanthus cusia
Bassia scoparia
bee products
bee propolis
berberine
Bidens pilosa
black cumin
black seed
blackboard tree
burdock
bасора
Calendula
cannabichromene
cannabigerol
Cannabis sativa oil
carvacrol
caryophyllene
castile soap
Centipeda
chamomile
chinatree
Chinese raisintree
chlorophyllin
chrysanthemum
Clerodendrum indicum
coconut
copaiba oil
cucumber
Curcuma
curcumen
curcumin
Curcuminoid
Dianthus
DIM (diindolylmethane)
Eclipta
epigallocatechin gallate (EGCG)
essential oil blend
estrogen
ethyl linoleate
eugenol
evening primrose oil
evening primrose oil
fatty acids
fulvic acid
gallic acid
garlic bulb
Glabridin
glyceryl monolaurate
Glycolic acid
green tea
heal-all
hemp
hemp oil
henna
herbal blend (proprietary)
Himalaya berry
honey
honeysuckle
Hydrocolloid
Immortelle
Indian fagonia
indigo leaves
Isatis
jojoba oil
Kigelia africana
Kokilaksha
L-cystine
Labdanum
lactic acid
Lactobacillus
Lactobacillus acidophilus
Lactobacillus casei
Lactobacillus plantarum
Lactobacillus reuteri
Lactobacillus rhamnosus
Lactoperoxidase
lauric acid
lavender
licorice root
Litsea
Mahonia
mangostin
Marking Nut Tree
melaleuca alternifolia
Melia
Momordica
Monolaurin
Monoterpenes
Morinda
Neem tree
Niacinamide (vitamin B3)
Nigella seed
omega-3 fatty acids
omega-6 fatty acids
oregon grape
oriental arborvitae
paederia foetida
Pansit-pansitan
pantothenic acid (vitamin B5)
Pentacyclic triterpenoids
Peptides
phenolic compounds
phlorotannins
probiotics
Propolis
scrophularia root
seaweed
Self-Heal
Sesquiterpenes
shen-chu
Shikonin
Smoketree
Soapberry
Sophora
Sphaeranthus indicus
Stellaria dichotoma
Tagetes
Tea Tree Oil
Terpenoids
Terpinen-4-ol
thyme
Thymol
Thymoquinone
Tinospora cordifolia
trace minerals
Triterpenes
turmeric
Viola
Violet
vitamin A
vitamin B
vitamin C
vitamin D
vitamin E
White Tea
Witch Hazel
Wrightia tinctoria
Xanthorrhizol
Zinc