Evidence supporting the use of: Ethyl Linoleate
For the health condition: Acne

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Synopsis

Source of validity: Scientific
Rating (out of 5): 3

Ethyl linoleate is an ester of linoleic acid, a polyunsaturated fatty acid known to play a role in skin health. Scientific research suggests that topical linoleic acid and its derivatives, including ethyl linoleate, may benefit acne-prone skin. Studies have found that individuals with acne have lower levels of linoleic acid in their skin surface lipids, which is thought to contribute to follicular hyperkeratosis and comedone formation. Supplementing the skin with linoleic acid derivatives may help restore the lipid barrier, reduce inflammation, and normalize keratinization.

One published study ("Topical Ethyl Linoleate Reduces Inflammation in Acne Vulgaris") found that topical application of ethyl linoleate can inhibit the production of pro-inflammatory mediators in sebocytes, the cells that produce sebum. This suggests an anti-inflammatory effect relevant to acne pathology. Additionally, ethyl linoleate may reduce sebum production and help prevent the formation of comedones. However, while these mechanisms are supported by laboratory and some clinical data, large-scale human trials are limited, and the ingredient is more commonly found in cosmeceuticals than in pharmaceutical treatments for acne.

In summary, there is emerging scientific evidence supporting the use of ethyl linoleate in acne management, particularly due to its anti-inflammatory properties and its role in restoring deficient skin lipids. The evidence, however, is moderate and primarily based on mechanistic studies and smaller clinical trials.

More about Ethyl Linoleate
More about Acne

Other health conditions supported by Ethyl Linoleate

Acne
Dermatitis
Eczema
Psoriasis

Products containing Ethyl Linoleate

We currently have no products on Vitabase that contain this ingredient.