Evidence supporting the use of: Eugenol
For the health condition: Acne

Links: Go back one page, Tool main page, Ingredients list, Health conditions list, Body systems list

Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Eugenol, a major component of clove oil, has been evaluated for its potential in treating acne primarily because of its antimicrobial and anti-inflammatory properties. Several in vitro studies have demonstrated that eugenol is effective against Propionibacterium acnes (now known as Cutibacterium acnes), the bacteria implicated in acne development. For example, research published in the journal Phytotherapy Research (2007) found that eugenol exhibited strong antibacterial activity against acne-causing bacteria. Additionally, eugenol has been shown to have anti-inflammatory effects, which could help reduce the redness and swelling associated with acne lesions.

However, most evidence supporting eugenol’s use in acne is limited to laboratory studies. There are few, if any, well-controlled clinical trials in humans directly demonstrating its efficacy or safety as a topical anti-acne treatment. Furthermore, eugenol is known to be a skin sensitizer and can cause allergic reactions or irritation, especially with repeated or high-concentration exposure. This risk limits its widespread use in dermatological formulations.

In summary, while there is some preliminary scientific evidence supporting eugenol’s activity against acne-related bacteria and inflammation, the current level of evidence is weak (rated 2/5) due to the lack of robust clinical data. Its use in acne treatment is not supported by substantial clinical validation, and safety concerns must be considered.

More about Eugenol
More about Acne

Other ingredients used for Acne

Ajoene
Aloe vera
alpha-pinene
berberine
bisabolol
black cumin
burdock
bасора
cannabis sativa oil
chamomile
cucumber
turmeric
curcumin
DIM (diindolylmethane)
epigallocatechin gallate (EGCG)
evening primrose oil
garlic bulb
green tea
hemp oil
honeysuckle
L-cystine
lactobacillus acidophilus
lactobacillus casei
lactobacillus reuteri
lactobacillus rhamnosus
lactoperoxidase
lauric acid
lavender
licorice root
monolaurin
niacinamide (Vitamin B3)
omega-3 fatty acids
omega-6 fatty acids
oregon grape
pantothenic acid (vitamin B5)
phenolic compounds
scrophularia root
sphaeranthus indicus
thyme
tomato
vitamin A
vitamin B
vitamin C
vitamin D
vitamin E
seaweed
zinc
shen-chu
neem tree
paederia foetida
tinospora cordifolia
blackboard tree
chrysanthemum
morinda
oriental arborvitae
trace minerals
anemarrhena asphodeloides
fulvic acid
herbal blend (proprietary)
melaleuca alternifolia
indigo leaves
15,16-Dihydrotanshinone I
Ash
Apple Cider Vinegar
Alpha-terpineol
Azelaic acid
Allicin
Abrus
Andrographolide
Alpha Hydroxy Acids
Allantoin
Asteracea
Argan nut oil
Anemarrhena
Bee Propolis
Black Seed
Babchi
Baphicacanthus cusia
Bidens pilosa
Banyan
Bee products
Bassia scoparia
Coconut
Caryophyllene
Calendula
Chlorophyllin
Carvacrol
Curcuminoid
Chinese Raisintree
Curcumen
Centipeda
Curcuma
Chinatree
Castile Soap
Copaiba Oil
Clerodendrum indicum
Cannabichromene
Cannabigerol
Dianthus
Eclipta
Essential Oil Blend
Evening Primrose Oil
Ethyl Linoleate
Eugenol
Estrogen
Fatty acids
Gallic Acid
Glycolic acid
Glyceryl monolaurate
Glabridin
Honey
Heal-All
Hydrocolloid
Henna
Himalaya Berry
Hemp
Isatis
Immortelle
Indian Fagonia
Jojoba Oil
Kigelia africana
Kokilaksha
Lactobacillus plantarum
Litsea
Lactic Acid
Lactobacillus
Labdanum
Melia
Monoterpenes
Mangostin
Momordica
Mahonia
Marking Nut Tree
Nigella Seed
Propolis
Pentacyclic triterpenoids
Phlorotannins
Probiotics
Pansit-pansitan
Peptides
Sophora
Sesquiterpenes
Shikonin
Self-Heal
Soapberry
Stellaria dichotoma
Sulfur
Smoketree
Terpenoids
Thymoquinone
Terpinen-4-ol
Triterpenes
Thymol
Tea Tree Oil
Tagetes
Violet
Viola
White Tea
Wrightia tinctoria
Witch Hazel
Xanthorrhizol

Products containing Eugenol

We currently have no products on Vitabase that contain this ingredient.