Evidence supporting the use of: Eugenol
For the health condition: Acne

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Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Eugenol, a major component of clove oil, has been evaluated for its potential in treating acne primarily because of its antimicrobial and anti-inflammatory properties. Several in vitro studies have demonstrated that eugenol is effective against Propionibacterium acnes (now known as Cutibacterium acnes), the bacteria implicated in acne development. For example, research published in the journal Phytotherapy Research (2007) found that eugenol exhibited strong antibacterial activity against acne-causing bacteria. Additionally, eugenol has been shown to have anti-inflammatory effects, which could help reduce the redness and swelling associated with acne lesions.

However, most evidence supporting eugenol’s use in acne is limited to laboratory studies. There are few, if any, well-controlled clinical trials in humans directly demonstrating its efficacy or safety as a topical anti-acne treatment. Furthermore, eugenol is known to be a skin sensitizer and can cause allergic reactions or irritation, especially with repeated or high-concentration exposure. This risk limits its widespread use in dermatological formulations.

In summary, while there is some preliminary scientific evidence supporting eugenol’s activity against acne-related bacteria and inflammation, the current level of evidence is weak (rated 2/5) due to the lack of robust clinical data. Its use in acne treatment is not supported by substantial clinical validation, and safety concerns must be considered.

More about eugenol
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Products containing eugenol

We currently have no products on Vitabase that contain this ingredient.