Evidence supporting the use of: Fulvic acid
For the health condition: Acne

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Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Fulvic acid has been explored as a potential treatment for acne, primarily due to its purported anti-inflammatory, antimicrobial, and antioxidant properties. The evidence supporting its use is limited but emerging, largely based on small-scale studies and in vitro research. One open-label clinical trial published in 2011 investigated a topical fulvic acid formulation in patients with mild to moderate eczema and acne; the study found some improvement in skin condition and reduced inflammation, attributed to fulvic acid’s ability to modulate cytokine activity and reduce microbial presence on the skin (Martin, 2011). In vitro studies have further demonstrated that fulvic acid can inhibit the growth of certain pathogens, including Propionibacterium acnes, which is implicated in the pathogenesis of acne. However, large, high-quality randomized controlled trials specifically investigating fulvic acid for acne are lacking. Most evidence comes from non-blinded or non-randomized studies, and the mechanisms of action remain incompletely understood. Traditional use of fulvic acid in folk medicine has centered around wound healing and general skin health rather than acne specifically. In summary, while there is some preliminary scientific evidence suggesting that fulvic acid may benefit people with acne, the overall quality and quantity of clinical data are limited. Thus, its use is best considered as adjunctive or experimental, pending further research.

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