Evidence supporting the use of: Glyceryl monolaurate
For the health condition: Acne

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Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Glyceryl monolaurate (GML), also known as monolaurin, is a monoglyceride derived from lauric acid and is recognized for its antimicrobial properties. Scientific studies have demonstrated that GML exhibits broad-spectrum antibacterial activity, including against various pathogens associated with skin infections. In the context of acne, the relevance of GML comes from its ability to inhibit the growth of Cutibacterium acnes (formerly Propionibacterium acnes), a bacterium implicated in the development of acne lesions. Laboratory studies have shown that GML can disrupt bacterial cell membranes and reduce the production of inflammatory mediators. Although these mechanistic and in vitro findings are promising, there is limited direct clinical evidence evaluating the efficacy of topical or oral GML in the treatment of acne in humans. Most available data are preclinical, consisting of cell culture and animal studies rather than randomized controlled trials in human subjects. GML is used in some topical formulations for its antimicrobial and emollient properties, but its specific effectiveness for acne treatment has not been robustly established through large-scale clinical studies. In summary, while there is a scientific rationale and some laboratory evidence supporting the use of glyceryl monolaurate for acne due to its antimicrobial effects, the current level of clinical evidence is limited. It is not a well-established or first-line treatment for acne, but ongoing research may further clarify its role.

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Products containing glyceryl monolaurate

We currently have no products on Vitabase that contain this ingredient.