Evidence supporting the use of: Isatis
For the health condition: Acne
Synopsis
Source of validity: Traditional
Rating (out of 5): 2
Isatis, particularly Isatis tinctoria (woad) and Isatis indigotica, has a longstanding role in traditional Chinese medicine (TCM). In TCM, Isatis root (Ban Lan Gen) and leaf (Da Qing Ye) are used for their "heat-clearing" and "detoxifying" properties. Acne, understood in TCM as a condition associated with "heat" and "toxicity" in the body, is sometimes treated with Isatis in combination with other herbs. Ancient and modern TCM texts commonly list Isatis extracts as components of herbal formulas for skin eruptions, pustular acne, and related inflammatory skin diseases. The evidence for these uses is based primarily on historical medical literature and practitioner anecdote rather than systematic scientific study.
Limited modern research has investigated Isatis extracts for their anti-inflammatory, antibacterial, and antiviral properties—mechanisms potentially relevant to acne. Some in vitro studies report that Isatis constituents, such as indirubin and tryptanthrin, may inhibit certain bacteria and reduce inflammation. However, robust clinical trials specifically assessing Isatis for acne are lacking. Thus, while there is some plausibility and a robust tradition of use, scientific validation remains insufficient, and the evidence is primarily traditional in nature.
Other ingredients used for Acne
ajoenealoe vera
alpha-pinene
berberine
bisabolol
black cumin
burdock
bасора
cannabis sativa oil
chamomile
cucumber
turmeric
curcumin
DIM (diindolylmethane)
epigallocatechin gallate (EGCG)
evening primrose oil
garlic bulb
green tea
hemp oil
honeysuckle
l-cystine
lactobacillus acidophilus
lactobacillus casei
lactobacillus reuteri
lactobacillus rhamnosus
lactoperoxidase
lauric acid
lavender
licorice root
monolaurin
niacinamide (vitamin B3)
omega-3 fatty acids
omega-6 fatty acids
oregon grape
pantothenic acid (vitamin B5)
phenolic acids
scrophularia root
sphaeranthus indicus
thyme
tomato
vitamin A
vitamin B
vitamin C
vitamin D
vitamin E
seaweed
zinc
shen-chu
neem tree
paederia foetida
tinospora cordifolia
blackboard tree
chrysanthemum
morinda
oriental arborvitae
trace minerals
anemarrhena asphodeloides
fulvic acid
herbal blend (proprietary)
melaleuca alternifolia
indigo leaves
15,16-Dihydrotanshinone I
Ash
Apple Cider Vinegar
Alpha-terpineol
Azelaic acid
Allicin
Abrus
Andrographolide
Alpha Hydroxy Acids
Allantoin
Asteracea
Argan nut oil
Anemarrhena
Bee Propolis
Black Seed
Babchi
Baphicacanthus cusia
Bidens pilosa
Banyan
Bee products
Bassia scoparia
Coconut
Caryophyllene
Calendula
Chlorophyllin
Carvacrol
Curcuminoid
Chinese Raisintree
Curcumen
Centipeda
Curcuma
Chinatree
Castile Soap
Copaiba Oil
Clerodendrum indicum
Cannabichromene
Cannabigerol
Dianthus
Eclipta
Essential Oil Blend
Evening Primrose Oil
Ethyl Linoleate
Eugenol
Estrogen
Other health conditions supported by Isatis
AbscessesAcne
Adenitis
Antibiotics (alternatives to)
Bronchitis
Cancer (natural therapy for)
Cancer (prevention)
Cancer Treatment (reducing side effects)
Carbuncles
Chills
Cholera
Colds (antiviral)
Colds (decongestant)
Colds (general)
Colds (prevention)
Colds (with fever)
Congestion
Congestion (bronchial)
Congestion (lungs)
Congestion (lymphatic)
Congestion (sinus)
Contagious Diseases
Cuts
Diphtheria
Eczema
Epstein Barr Virus
Eye Infections
Fever
Gangrene
Gastritis
Gingivitis
Glands (swollen lymph)
Gonorrhea
Herpes