Kokilaksha (Asteracantha longifolia, also known as Hygrophila auriculata) is primarily recognized in traditional Ayurvedic medicine for its diuretic, hepatoprotective, and anti-inflammatory properties. In Ayurveda, it is occasionally mentioned as a supportive herb for skin health due to its purported ability to balance the pitta dosha, which is often associated with inflammatory skin conditions like acne. Some classical Ayurvedic texts refer to its use in formulations aimed at purifying the blood and treating various skin ailments, which may include acne as a symptom of internal imbalance.

However, the specific use of Kokilaksha for acne is not prominent in historical Ayurvedic literature compared to other herbs such as Neem or Manjistha. The rationale for its use rests on its general anti-inflammatory and detoxifying actions as understood in traditional practice, rather than direct evidence or targeted recommendations for acne treatment.

Scientific research on Kokilaksha has mostly focused on its hepatoprotective and diuretic effects, with only limited studies addressing its antimicrobial or anti-inflammatory actions relevant to acne. There is a lack of robust clinical trials or preclinical studies directly evaluating its efficacy for acne vulgaris. Thus, while there is some traditional precedent for its use in skin disorders, the evidence base is limited, and stronger scientific validation is lacking.