Evidence supporting the use of: Lactobacillus
For the health condition: Acne

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Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Lactobacillus, a genus of probiotic bacteria commonly found in fermented foods and supplements, has been investigated for its potential role in supporting or treating acne. Scientific interest arises from the understanding that the gut microbiome can influence skin health through the "gut-skin axis." Several small clinical trials and preclinical studies have explored the effects of oral and topical Lactobacillus strains on acne severity. For example, a few randomized controlled trials (RCTs) have shown modest improvements in acne lesions and inflammation when probiotics containing Lactobacillus (often combined with Bifidobacterium) were administered for several weeks. The proposed mechanisms include modulation of systemic and local inflammation, regulation of immune responses, and inhibition of pathogenic skin bacteria such as Cutibacterium acnes. Additionally, topical formulations containing Lactobacillus lysate have demonstrated anti-inflammatory and barrier-supporting properties in limited studies.

However, the overall quality of the evidence is low to moderate: sample sizes are small, many studies lack robust controls, and there is significant heterogeneity in probiotic strains and formulations used. Meta-analyses suggest a possible benefit but stress the need for larger, well-designed trials. Thus, while there is some scientific rationale and early clinical evidence for the use of Lactobacillus in managing acne, it is not yet considered a standard or primary therapy, and further validation is required.

More about Lactobacillus
More about Acne

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epigallocatechin gallate (EGCG)
essential oil blend
estrogen
ethyl linoleate
eugenol
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fatty acids
fulvic acid
gallic acid
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glyceryl monolaurate
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green tea
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henna
herbal blend (proprietary)
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Products containing Lactobacillus

We currently have no products on Vitabase that contain this ingredient.