Evidence supporting the use of: Lactobacillus
For the health condition: Acne

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Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Lactobacillus, a genus of probiotic bacteria commonly found in fermented foods and supplements, has been investigated for its potential role in supporting or treating acne. Scientific interest arises from the understanding that the gut microbiome can influence skin health through the "gut-skin axis." Several small clinical trials and preclinical studies have explored the effects of oral and topical Lactobacillus strains on acne severity. For example, a few randomized controlled trials (RCTs) have shown modest improvements in acne lesions and inflammation when probiotics containing Lactobacillus (often combined with Bifidobacterium) were administered for several weeks. The proposed mechanisms include modulation of systemic and local inflammation, regulation of immune responses, and inhibition of pathogenic skin bacteria such as Cutibacterium acnes. Additionally, topical formulations containing Lactobacillus lysate have demonstrated anti-inflammatory and barrier-supporting properties in limited studies.

However, the overall quality of the evidence is low to moderate: sample sizes are small, many studies lack robust controls, and there is significant heterogeneity in probiotic strains and formulations used. Meta-analyses suggest a possible benefit but stress the need for larger, well-designed trials. Thus, while there is some scientific rationale and early clinical evidence for the use of Lactobacillus in managing acne, it is not yet considered a standard or primary therapy, and further validation is required.

More about Lactobacillus
More about Acne

Other ingredients used for Acne

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alpha-pinene
berberine
bisabolol
black cumin
burdock
bасора
cannabis sativa oil
chamomile
cucumber
turmeric
curcumin
DIM (diindolylmethane)
epigallocatechin gallate (EGCG)
evening primrose oil
garlic bulb
green tea
hemp oil
honeysuckle
L-cystine
lactobacillus acidophilus
lactobacillus casei
lactobacillus reuteri
lactobacillus rhamnosus
lactoperoxidase
lauric acid
lavender
licorice root
monolaurin
niacinamide (Vitamin B3)
omega-3 fatty acids
omega-6 fatty acids
oregon grape
pantothenic acid (vitamin B5)
phenolic compounds
scrophularia root
sphaeranthus indicus
thyme
tomato
vitamin A
vitamin B
vitamin C
vitamin D
vitamin E
seaweed
zinc
shen-chu
neem tree
paederia foetida
tinospora cordifolia
blackboard tree
chrysanthemum
morinda
oriental arborvitae
trace minerals
anemarrhena asphodeloides
fulvic acid
herbal blend (proprietary)
melaleuca alternifolia
indigo leaves
15,16-Dihydrotanshinone I
Ash
Apple Cider Vinegar
Alpha-terpineol
Azelaic acid
Allicin
Abrus
Andrographolide
Alpha Hydroxy Acids
Allantoin
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Anemarrhena
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Black Seed
Babchi
Baphicacanthus cusia
Bidens pilosa
Banyan
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Bassia scoparia
Coconut
Caryophyllene
Calendula
Chlorophyllin
Carvacrol
Curcuminoid
Chinese Raisintree
Curcumen
Centipeda
Curcuma
Chinatree
Castile Soap
Copaiba Oil
Clerodendrum indicum
Cannabichromene
Cannabigerol
Dianthus
Eclipta
Essential Oil Blend
Evening Primrose Oil
Ethyl Linoleate
Eugenol
Estrogen
Fatty acids
Gallic Acid
Glycolic acid
Glyceryl monolaurate
Glabridin
Honey
Heal-All
Hydrocolloid
Henna
Himalaya Berry
Hemp
Isatis
Immortelle
Indian Fagonia
Jojoba Oil
Kigelia africana
Kokilaksha
Lactobacillus plantarum
Litsea
Lactic Acid
Lactobacillus
Labdanum
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Monoterpenes
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Mahonia
Marking Nut Tree
Nigella Seed
Propolis
Pentacyclic triterpenoids
Phlorotannins
Probiotics
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Peptides
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Products containing Lactobacillus

We currently have no products on Vitabase that contain this ingredient.