Evidence supporting the use of: Phlorotannins
For the health condition: Acne

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Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Phlorotannins are polyphenolic compounds derived from brown seaweeds, and recent research has explored their potential benefits in dermatology, including acne treatment. The scientific rationale for using phlorotannins to support or treat acne is based on their demonstrated anti-inflammatory, antioxidant, and antibacterial properties. In vitro studies have shown that phlorotannins can inhibit the growth of Cutibacterium acnes (formerly Propionibacterium acnes), the bacterium involved in acne pathogenesis. Additionally, phlorotannins have been reported to reduce sebum production and suppress inflammatory cytokine expression in skin cells, both of which are relevant mechanisms in acne development.

However, the evidence supporting the use of phlorotannins for acne is still preliminary and largely limited to laboratory and animal studies. There are few, if any, well-conducted human clinical trials directly assessing the efficacy of phlorotannins for acne treatment. As such, while the scientific basis is promising and mechanistically sound, clinical validation is currently lacking. Overall, the use of phlorotannins for acne can be considered as supported by early-stage scientific evidence, but more robust human data are needed before it can be recommended as a reliable treatment.

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Products containing Phlorotannins

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