Evidence supporting the use of: Sulfur
For the health condition: Acne

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Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Sulfur has a long history of use in dermatology, including for the treatment of acne. Its application dates back centuries, making it both a traditional and scientific remedy. However, its modern use is supported primarily by its well-established pharmacological properties. Sulfur acts as a keratolytic agent, meaning it helps to shed the outer layer of skin, and as a mild antimicrobial. These effects are helpful in managing acne, which involves blocked pores and bacterial colonization.

Clinical evidence supporting sulfur’s efficacy for acne is limited but present. Several small studies and reviews note that sulfur, often in combination with other agents (such as resorcinol or sodium sulfacetamide), can reduce acne lesions. Its standalone efficacy is generally considered modest compared to other topical agents like benzoyl peroxide or retinoids. Most guidelines regard sulfur as a secondary or adjunctive treatment, particularly for patients with sensitive skin or those who cannot tolerate stronger medications.

Overall, while sulfur’s anti-acne effects are supported by plausible mechanisms and some clinical observations, robust, large-scale randomized controlled trials are lacking. Therefore, the evidence is rated as moderate (2/5), reflecting its established use but limited high-quality scientific validation.

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Products containing Sulfur

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