Evidence supporting the use of: Sulphur
For the health condition: Acne

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Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Sulphur has been used for centuries in the treatment of acne, with both historical and modern applications. Its use is supported by scientific evidence, though the quality and quantity of studies are limited and generally low in rigor. Sulphur possesses keratolytic (exfoliating) and antibacterial properties, which are believed to help in the treatment of acne by promoting the shedding of dead skin cells and reducing the population of acne-causing bacteria on the skin.

Several clinical guidelines and dermatology textbooks acknowledge sulphur's role, particularly in mild to moderate acne and in combination with other agents such as resorcinol or sodium sulfacetamide. The mechanism of action is thought to involve the breakdown of keratin, which helps unclog pores, and its mild antimicrobial effect, which may reduce Cutibacterium acnes (formerly Propionibacterium acnes).

However, high-quality randomized controlled trials are lacking, and most available data are from older studies, small case series, or expert opinion. As such, the evidence base is weak (rated 2/5), but its long history of use and inclusion in over-the-counter products lend some support to its efficacy and safety profile for mild forms of acne. Side effects such as dryness and irritation are common, and sulphur is less commonly used today compared to other agents like benzoyl peroxide or retinoids.

More about Sulphur
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Products containing Sulphur

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