Evidence supporting the use of: Thymoquinone
For the health condition: Acne

Links: Go back one page, Tool main page, Ingredients list, Health conditions list, Body systems list

Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Thymoquinone is a bioactive compound found in the seeds of Nigella sativa (black seed). There is emerging scientific interest in its potential to support the treatment of acne, primarily due to its demonstrated anti-inflammatory, antioxidant, and antimicrobial properties. Several in vitro studies have shown that thymoquinone can inhibit the growth of Propionibacterium acnes (now known as Cutibacterium acnes), the bacterium implicated in acne pathogenesis. Additionally, thymoquinone has been shown to suppress the production of pro-inflammatory cytokines and reduce oxidative stress in skin cells, both of which are relevant mechanisms in the development of acne lesions.

However, while these effects are promising, most of the evidence comes from laboratory and animal studies. Clinical research involving human subjects with acne is limited, with only a few small-scale studies or case reports evaluating topical formulations containing Nigella sativa or thymoquinone. These preliminary trials have noted some improvement in acne severity, but the studies are often limited by small sample sizes and lack of rigorous controls. Overall, while thymoquinone's use for acne has a plausible scientific basis and some supporting laboratory data, robust clinical evidence is lacking. Larger, well-designed clinical trials are needed to firmly establish its efficacy and safety for acne treatment.

More about Thymoquinone
More about Acne

Other ingredients used for Acne

15,16-Dihydrotanshinone I
Abrus
Ajoene
Allantoin
Allicin
Aloe vera
Alpha hydroxy acids
alpha-pinene
alpha-terpineol
andrographolide
Anemarrhena
anemarrhena asphodeloides
apple cider vinegar
argan nut oil
ash
Asteraceae
azelaic acid
babchi
banyan
Baphicacanthus cusia
Bassia scoparia
bee products
bee propolis
berberine
Bidens pilosa
black cumin
black seed
blackboard tree
burdock
bасора
Calendula
cannabichromene
cannabigerol
Cannabis sativa oil
carvacrol
caryophyllene
castile soap
Centipeda
chamomile
chinatree
Chinese raisintree
chlorophyllin
chrysanthemum
Clerodendrum indicum
coconut
copaiba oil
cucumber
Curcuma
curcumen
curcumin
Curcuminoid
Dianthus
DIM (diindolylmethane)
Eclipta
epigallocatechin gallate (EGCG)
essential oil blend
estrogen
ethyl linoleate
eugenol
evening primrose oil
evening primrose oil
fatty acids
fulvic acid
gallic acid
garlic bulb
Glabridin
glyceryl monolaurate
Glycolic acid
green tea
heal-all
hemp
hemp oil
henna
herbal blend (proprietary)
Himalaya berry
honey
honeysuckle
Hydrocolloid
Immortelle
Indian fagonia
indigo leaves
Isatis
jojoba oil
Kigelia africana
Kokilaksha
L-cystine
Labdanum
lactic acid
Lactobacillus
Lactobacillus acidophilus
Lactobacillus casei
Lactobacillus plantarum
Lactobacillus reuteri
Lactobacillus rhamnosus
Lactoperoxidase
lauric acid
lavender
licorice root
Litsea
Mahonia
mangostin
Marking Nut Tree
melaleuca alternifolia
Melia
Momordica
Monolaurin
Monoterpenes
Morinda
Neem tree
Niacinamide (vitamin B3)
Nigella seed
omega-3 fatty acids
omega-6 fatty acids
oregon grape
oriental arborvitae
paederia foetida
Pansit-pansitan
pantothenic acid (vitamin B5)
Pentacyclic triterpenoids
Peptides
phenolic compounds
phlorotannins
probiotics
Propolis
scrophularia root
seaweed
Self-Heal
Sesquiterpenes
shen-chu
Shikonin
Smoketree
Soapberry
Sophora
Sphaeranthus indicus
Stellaria dichotoma
Tagetes
Tea Tree Oil
Terpenoids
Terpinen-4-ol
thyme
Thymol
Thymoquinone
Tinospora cordifolia
trace minerals
Triterpenes
turmeric
Viola
Violet
vitamin A
vitamin B
vitamin C
vitamin D
vitamin E
White Tea
Witch Hazel
Wrightia tinctoria
Xanthorrhizol
Zinc

Products containing Thymoquinone

We currently have no products on Vitabase that contain this ingredient.