Evidence supporting the use of: Vitamin B5 (mixed)
For the health condition: Acne

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Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Vitamin B5 (pantothenic acid) has some emerging scientific evidence supporting its use in acne treatment, though the body of research is limited and of mixed quality. A few small clinical trials, most notably a randomized controlled trial published in 2014 in Dermatology and Therapy, found that supplementation with pantothenic acid significantly reduced total facial acne lesions compared to placebo over a 12-week period. Proposed mechanisms include pantothenic acid’s role in lipid metabolism and its potential to reduce sebum production, a major factor in acne development. Additionally, it may help enhance skin barrier function and modulate inflammation, though these effects have not been extensively studied in the context of acne.

Despite these findings, the overall evidence remains preliminary. Most studies have small sample sizes, short durations, and potential conflicts of interest. Systematic reviews and dermatological guidelines do not currently recognize vitamin B5 as a standard or well-supported treatment for acne. Historically, vitamin B5 has not been a part of traditional remedies for acne, and its use is primarily based on recent scientific hypotheses and early-stage clinical trials. In summary, while there is some scientific rationale and limited clinical evidence suggesting potential benefit, more robust, large-scale studies are needed before vitamin B5 can be considered a validated treatment for acne.

More about Vitamin B5 (mixed)
More about Acne

Other health conditions supported by Vitamin B5 (mixed)

Acne
Burning Feet or Hands
Burns and Scalds
Cholesterol (high)
Cuts
Dermatitis

Products containing Vitamin B5 (mixed)

We currently have no products on Vitabase that contain this ingredient.