Evidence supporting the use of: Vitamin C (mixed)
For the health condition: Acne

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Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Vitamin C (ascorbic acid), particularly in topical formulations, has some scientific evidence supporting its use in the management of acne, although the evidence is limited and not as robust as for other treatments like retinoids or benzoyl peroxide. Vitamin C is known for its antioxidant properties and its role in collagen synthesis, which may help in skin repair and reducing post-inflammatory hyperpigmentation associated with acne. Some studies suggest that topical vitamin C can reduce inflammation, inhibit melanin production, and improve skin barrier function. For example, small clinical trials have shown that vitamin C serums may help in reducing acne lesions and improving overall skin texture when used as an adjunct to standard treatments. However, oral vitamin C supplementation does not have strong evidence for acne control, and most benefits are attributed to topical application. The use of "mixed" Vitamin C, referring to formulations containing different derivatives (such as magnesium ascorbyl phosphate or ascorbyl glucoside), may enhance stability and skin penetration, but direct evidence comparing different forms for acne is sparse. Overall, while there is a scientific rationale and some preliminary data supporting the topical use of vitamin C for acne, especially for managing pigmentation and inflammation, the quality and quantity of evidence are modest, so it should not be considered a primary therapy.

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Products containing Vitamin C (mixed)

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