Evidence supporting the use of: Cannabis sativa oil
For the health condition: Acquired Immune Deficiency Syndrome

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Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Cannabis sativa oil, which contains cannabinoids such as THC and CBD, has been explored as an adjunct therapy for individuals living with Acquired Immune Deficiency Syndrome (AIDS). Historically, cannabis has been used in various cultures for its medicinal properties, but its specific use for HIV/AIDS-related symptoms is relatively recent and primarily rooted in scientific investigation rather than longstanding tradition. Clinical research in the modern era has focused on cannabis’ potential to alleviate symptoms associated with HIV/AIDS, especially in the context of wasting syndrome (involuntary weight loss), nausea, pain, and appetite loss. Some studies have demonstrated that cannabinoids can stimulate appetite and improve caloric intake in HIV/AIDS patients, which can be beneficial for those experiencing cachexia. Additionally, cannabis may provide relief from neuropathic pain and nausea, both common in HIV/AIDS and its treatments. However, the evidence is limited by small sample sizes, variability in study design, and legal restrictions on cannabis research. While cannabinoids are not shown to directly treat the underlying viral infection, their symptomatic relief has led to the approval of synthetic THC (dronabinol) for AIDS-related anorexia in some jurisdictions. Overall, while there is some scientific support for the use of cannabis sativa oil in managing certain symptoms of AIDS, the evidence remains moderate, and further rigorous research is necessary to clarify its efficacy and safety profile.

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