Evidence supporting the use of: Caterpillar mushroom
For the health condition: Acquired Immune Deficiency Syndrome

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Synopsis

Source of validity: Traditional
Rating (out of 5): 2

Caterpillar mushroom, also known as Cordyceps sinensis or Ophiocordyceps sinensis, has a long history of use in traditional Chinese and Tibetan medicine. It has been prized for its purported ability to boost vitality, improve stamina, and support immune function. In the context of Acquired Immune Deficiency Syndrome (AIDS), its use is primarily justified by tradition rather than robust scientific validation. Historical records and traditional practice suggest that Cordyceps was administered to individuals with symptoms consistent with immune deficiency, such as chronic fatigue and recurrent infections, although the term "AIDS" was not used in ancient texts. The rationale behind its use for immune support comes from its adaptogenic and immunomodulatory properties described in traditional medicine. Some preclinical studies and small-scale clinical trials have explored the effects of Cordyceps extracts on immune cell activity, cytokine production, and general health in immunocompromised individuals. However, these studies are limited in size, often lack rigorous controls, and do not directly address efficacy in HIV/AIDS patients. No large, well-controlled clinical trials have definitively demonstrated that Cordyceps can treat or significantly improve outcomes in people with AIDS. In summary, while Cordyceps mushroom is traditionally used to support immune health and may be used by some as a complementary therapy for AIDS, current evidence supporting its efficacy for this condition is weak and primarily based on traditional use rather than high-quality scientific research.

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