Evidence supporting the use of: Momordica (unspecified)
For the health condition: Acquired Immune Deficiency Syndrome

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Synopsis

Source of validity: Traditional
Rating (out of 5): 1

Momordica, particularly Momordica charantia (bitter melon), has been used in traditional medicine systems for a variety of conditions, including infections and immune-related disorders. In some regions, traditional healers have used bitter melon preparations in attempts to support patients with Acquired Immune Deficiency Syndrome (AIDS) or HIV, largely based on the plant’s general reputation for immune modulation and antiviral activity. However, these uses are primarily anecdotal and not based on robust clinical evidence.

Scientific studies on Momordica spp. have identified compounds such as MAP30 (Momordica anti-HIV protein of 30 kDa), which demonstrated in vitro activity against HIV-1 by inhibiting viral replication. These laboratory findings generated interest in the potential of Momordica extracts for HIV/AIDS management. Despite such preliminary findings, subsequent research has not provided solid clinical evidence to support the efficacy or safety of Momordica for treating or supporting patients with AIDS. No large-scale, peer-reviewed clinical trials have confirmed benefits in humans with HIV/AIDS, and current medical guidelines do not recognize Momordica as an effective therapy for this condition.

In summary, the use of Momordica for AIDS is rooted in traditional practices and early laboratory studies, but the supporting evidence is limited and primarily preclinical, with no substantial clinical validation to justify its use for this purpose.

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